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Are There Vitamins for PE?

By Linda Tarr Kent

While premature ejaculation, or PE, is a common complaint, this condition is rarely caused by a physical problem. Practice and relaxation are usually recommended for dealing with this issue, in which the man ejaculates sooner than he or his partner would like. Too much stimulation, anxiety or guilt is often the root of the problem, according to PubMed Health. Despite the lack of physical causes, supplements promising to alleviate PE abound. Consult a doctor before taking any supplement to combat PE.

B Vitamins

Formulations for premature ejaculation typically include B vitamins. Folic acid is especially helpful, according to “Doc Herb’s Plant Survivalist,” by Douglas Walf. B vitamins help boost overall health and also help combat stress and anxiety, notes "Eco-Sex" author Stefanie Iris Weiss. The recommended daily amount, or RDA, for folic acid is 400 mcg, and the upper limit is 1,000 mcg.


Premature ejaculation in some cases is linked to high histamine levels, according to “Super Nutrition for Men,” by Ann Louise Gittleman. Histamine causes inflammation in the body and is involved in allergic reactions. The author advises supplementing with calcium to help lower histamine levels. The RDA for calcium for men up to age 50 is 1,000 mg. For ages 51 and older, it’s 1,200 mg. The upper limit is 2,500 mg.

The amino acid methionine also may help lower blood histamine levels, Gittleman notes. However, consult a doctor and use caution if you are interested in supplemental methionine, because it can raise homocysteine levels. Elevated homocysteine levels are associated with a raised risk for heart attack and stroke. Supplementing with folate may prevent elevated homocysteine due to methionine supplementation, notes a 2005 “European Journal of Clinical Nutrition Study.”

Other Vitamins

Vitamin formulations that include vitamin E, magnesium and zinc also are purportedly helpful if you are having problems with premature ejaculation. Vitamin E has a suggested albeit unproven benefit, because deficiency in this vitamin leads to impaired reproductive ability, notes “Pharmacology for Health Professionals,” by Bronwen Jean Bryant and Kathleen Mary Knights. Reduced concentrations of magnesium in semen are associated with PE, according to “Male Infertility,” by Anne M. Jequier. The purported benefit from zinc is linked to the fact that zinc also is present in semen.

Recommended vitamin E intake for men is 15 mg, and the upper limit is 1,000 mg. The RDA for zinc is 11 mg, and the upper limit is 40 mg. The RDA for dietary magnesium is 420 mg. The upper limit, which applies only to supplemental magnesium and not to dietary magnesium, is 350 mg, according to Harvard Medical School.


Supplements for PE also typically include herbs such as maca, yohimbe and passionflower. However, supplements designed to combat PE don’t have any good clinical evidence to back them, according to Ian Kerner, author of “Good in Bed Guide to Overcoming Premature Ejaculation." Consult your doctor before trying supplements, even they are vitamins, and follow his advice for dosage. Taking too much zinc, for example, can interfere with your body’s ability to absorb the mineral copper. Meanwhile, high levels of dietary calcium theoretically impair zinc absorption, and supplemental iron may also decrease zinc absorption. Zinc and copper are both essential for humans.

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