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- Medline Plus: Milk Thistle
- Herbal Medicine: Biomolecular and Clinical Aspects; Philip D. Shenefelt
- Herbal Medicine: Biomolecular and Clinical Aspects; Philip D. Shenefelt
- PubMed: Immunostimulatory Effect of Silybum Marianum (Milk Thistle) Extract
- PubMed: Immunostimulatory Effect of Silybum Marianum (Milk Thistle) Extract
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Can Milk Thistle Help Hair Loss?
Milk thistle, also called lady's thistle, has a long history of use. It's considered possibly effective in easing heartburn and seasonal allergies when used with other herbs, according to Medline Plus. Milk thistle and one of its substances, a flavonoid called silymarin, are being studied widely for potential use in treating liver disease and tumor growth, although there's insufficient evidence of effectiveness 2. Some hair-growth products contain milk thistle as an ingredient, but there's no evidence they will help hair grow or stop hair loss.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Thin Evidence for Hair Connection
One hair-growth formula includes milk thistle along with 21 other ingredients, stating that the herb's antioxidants protect hair follicles. Milk thistle extract from plants -- not the seeds -- might, in fact, enhance effects of estrogen, Medline Plus says. But estrogen's role in hair loss is not completely understood. While milk thistle's effects are being widely studied in treating liver and other diseases, its role in hair loss -- whether for topical or oral use -- has not yet been studied 2. Milk thistle is generally thought safe to take, with mild side effects including stomach upset. Don't take it if you're pregnant or breast-feeding, or have health conditions or take medicines that effect estrogen; check with your doctor before taking it if you use any medications.
- One hair-growth formula includes milk thistle along with 21 other ingredients, stating that the herb's antioxidants protect hair follicles.
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References
- Herbal Medicine: Biomolecular and Clinical Aspects; Philip D. Shenefelt
- Cancer Research UK: Milk Thistle and Liver Cancer
- University of Maryland Medical Center: Alopecia
- EWG's Skin Deep Cosmetics Database: Silybum Marianum (Lady'sThistle) Extract
- PubMed: Immunostimulatory Effect of Silybum Marianum (Milk Thistle) Extract
- University of Maryland Medical Center: Milk Thistle
- National Center for Complementary and Integrative Health. Milk Thistle. Updated September 2016.
- Abenavoli L, Capasso R, Milic N, Capasso F. Milk thistle in liver diseases: past, present, future. Phytother Res. 2010;24(10):1423-32. doi:10.1002/ptr.3207
- Salmi HA, Sarna S. Effect of silymarin on chemical, functional, and morphological alterations of the liver. A double-blind controlled study. Scand J Gastroenterol. 1982;17(4):517-21. doi:10.3109/00365528209182242
- Seeff LB, Curto TM, Szabo G, et al. Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. Hepatology. 2008;47(2):605-12. doi:10.1002/hep.22044
- Fried MW, Navarro VJ, Afdhal N, et al. Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. JAMA. 2012;308(3):274-82. doi:10.1001/jama.2012.8265
- Ebrahimpour koujan S, Gargari BP, Mobasseri M, Valizadeh H, Asghari-jafarabadi M. Effects of Silybum marianum (L.) Gaertn. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. Phytomedicine. 2015;22(2):290-6. doi:10.1016/j.phymed.2014.12.010
- Kazazis CE, Evangelopoulos AA, Kollas A, Vallianou NG. The therapeutic potential of milk thistle in diabetes. Rev Diabet Stud. 2014;11(2):167-74. doi:10.1900/RDS.2014.11.167
- Ebrahimpour, K.; Gargari, B.; Mobasseri, M. et al. Effects of Silybum marianum (L.) Gaertn. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. Phytomedicine. 2015 Feb 15;22(2):290-6. DOI: 10.1016/j.phymed.2014.12.010.
- Fried, M.; Navarro, V.; Afdhal, N. et al. Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. JAMA. 2012 Jul 18;308(3):274-82. DOI: 10.1001/jama.2012.8265.
- Rambaldi, A.; Jacobs, B.; Iaquinto G, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C liver diseases--a systematic Cochrane hepato-biliary group review with meta-analyses of randomized clinical trials. Am J Gastroenterol. 2005 Nov;100(11):2583-91. DOI: 10.1111/j.1572-0241.2005.00262.x.
- Salmi, H. and Sarna, S. Effect of silymarin on chemical, functional, and morphological alterations of the liver. A double-blind controlled study. Scan J Gastroenterol. 1982;17:517–21.
- Seeff, L.; Curto, T.; Szabo, G. et al. Herbal product use by persons enrolled in the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. Hepatology. 2008;47(2):605-12. DOI: 10.1002/hep.22044.
- Voroneanu, L.; Nistor, I.; Dumea, R. et al. Silymarin in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Diabetes Res. 2016;2016:5147468. DOI: 10.1155/2016/5147468.
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Bonny Brown Jones has been a writer, columnist, copy editor and senior copy editor for newspapers that have included the "Orlando Sentinel," "Miami Herald" and "Columbus (Ohio) Dispatch." Jones has a Bachelor of Arts in English from Ohio State University.