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Zinc is a mineral that is essential for the function of the body. However, zinc supplements can interfere with the effects of different medications, including some antibiotics, by reducing their absorption 1. Although zinc does not appear to interfere with the activity of doxycycline, you should still talk to your doctor about all minerals that you take if you are prescribed an antibiotic 2.
Why Take Zinc?
Zinc is a mineral that is needed in small quantities for your body to function properly. Zinc has many roles in the body, including aiding in cell division, DNA synthesis, protein synthesis, wound healing and the immune system. You may take zinc supplements to boost your immune system and to help you fight off infection 1. Zinc can also be found in some antacids that are used to fight indigestion and heartburn.
- Zinc is a mineral that is needed in small quantities for your body to function properly.
- You may take zinc supplements to boost your immune system and to help you fight off infection 1.
Acid Reflux & Zinc
Doxycycline is an antibiotic that is related to tetracycline, another antibiotic 2. Doxycycline treats many bacterial infections, including urinary tract infections, gonorrhea, gum disease, chlamydia and bacteria that trigger acne 2. Doxycycline can interact with different medications, including birth control, and make them less effective 2. Drugs.com recommends that people taking doxycycline avoid using this medication along with zinc supplements, due to the potential for zinc to interact with this drug 12.
Zinc and Doxycycline
One of the reasons why doctors often advise against taking zinc with antibiotics is that zinc can inhibit the absorption of many antibiotics. However, the recommendation against taking zinc with doxycycline may be due to zinc's reputation as a mineral that affects antibiotic effectiveness, but a study published in a 1975 issue of the "European Journal of Clinical Pharmacology" found that zinc supplements did not significantly inhibit the absorption of doxycycline 12.
Effects of Doxycycline on Periods
Tell your doctor about any mineral or vitamin supplements that you are taking, particularly if your doctor prescribes a new medication for you. The benefits of zinc supplements for infections are controversial, and it is important to not impair the effectiveness of antibiotics and other medications that you take 1. Check with your doctor before starting or stopping a supplement.
Acid Reflux & Zinc
Effects of Doxycycline on Periods
Garlic vs. Penicillin
Acidophilus & Gastritis
Side Effects of Zinc Lozenges
Vitamin C & Amoxicillin
What Are the Benefits of Zinc Gluconate for Skin?
Antibiotics Recommended for Infected Wounds
Does Alcohol Affect Doxycycline?
Does Calcium Affect Antibiotics?
- Office of Dietary Supplements: Zinc
- Drugs.com: Doxycycline
- National Institutes of Health. Office of Dietary Supplements. Zinc Fact Sheet for Health Professionals. Updated March 6, 2020.
- Wessels I, Maywald M, Rink L. Zinc as a Gatekeeper of Immune Function. Nutrients. 2017;9(12):1286. doi:10.3390/nu9121286
- Mousa HA. Prevention and Treatment of Influenza, Influenza-Like Illness, and Common Cold by Herbal, Complementary, and Natural Therapies. J Evid Based Complementary Altern Med. 2017;22(1):166-174. doi:10.1177/2156587216641831
- Krebs NF, Miller LV, Hambidge KM. Zinc deficiency in infants and children: a review of its complex and synergistic interactions. Paediatr Int Child Health. 2014;34(4):279-288. doi:10.1179/2046905514Y.0000000151
- Gogia S, Sachdev HS. Zinc supplementation for mental and motor development in children. Cochrane Database Syst Rev. 2012;12:CD007991. doi:10.1002/14651858.CD007991.pub2
- Ogawa Y, Kinoshita M, Shimada S, Kawamura T. Zinc and Skin Disorders. Nutrients. 2018;10(2):199. doi:10.3390/nu10020199
- Gupta M, Mahajan VK, Mehta KS, Chauhan PS. Zinc Therapy in Dermatology: A Review. Dermatol Res Pract. 2014;2014:709152. doi:10.1155/2014/709152
- Khan WU, Sellen DW. World Health Organization. Zinc supplementation in the management of diarrhoea. 2011.
- Petrilli MA, Kranz TM, Kleinhaus K, et al. The Emerging Role for Zinc in Depression and Psychosis. Front Pharmacol. 2017;8:414. doi:10.3389/fphar.2017.00414
- Fallah A, Mohammad-Hasani A, Colagar AH. Zinc is an Essential Element for Male Fertility: A Review of Zn Roles in Men's Health, Germination, Sperm Quality, and Fertilization. J Reprod Infertil. 2018;19(2):69‐81.
- Zhao J, Dong X, Hu X, et al. Zinc levels in seminal plasma and their correlation with male infertility: A systematic review and meta-analysis. Sci Rep. 2016;6:22386. Published 2016 Mar 2. doi:10.1038/srep22386
- U.S. Department of Agriculture, Agricultural Research Service. Oysters, Raw. FoodData Central. Updated 2020.
Adam Cloe has been published in various scientific journals, including the "Journal of Biochemistry." He is currently a pathology resident at the University of Chicago. Cloe holds a Bachelor of Arts in biochemistry from Boston University, a M.D. from the University of Chicago and a Ph.D. in pathology from the University of Chicago.