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Calcium Phosphate Supplement Side Effects

By Heather Topham Wood

Calcium phosphate is an oral form of vitamin D3. It is given as a way to treat calcium deficiency as well as promote bone health in people with degenerative diseases, like osteoporosis. You are typically instructed to consume calcium-rich meals while taking the supplement in order to improve absorption. If you have any side effects while taking calcium phosphate, you should notify your doctor right away.

Allergic Reaction

It is possible to develop an allergic reaction when taking a calcium phosphate supplement. Stop taking the drug immediately and notify a doctor if you experience any of these side effects: difficulty breathing, facial swelling, mouth swelling, itching, dizziness or hives.

Upset Stomach

You can experience digestive issues when taking a calcium phosphate supplement. Vitamin D3 can cause vomiting, nausea, loss of appetite and constipation. Sudden weight loss can also be a side effect of the drug.

Urinary Tract

Your urinary tract can also be affected by calcium phosphate. Supplemental doses of vitamin D3 can cause changes in the amount of urine outputted as well as an increased need to pee. These side effects can also be related to the increased thirst that can result from calcium phosphate supplementation.


Although rare, you can feel fatigued after taking calcium phosphate supplements. It can also potentially cause weakness. Mood changes can occur when taking the drug.

Aches and Pains

Body aches and pains is a side effect of the oral form of vitamin D3. Your bones and muscles may have an achy feeling. Headache is another reported side effect of the drug.

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