The most predominant cause of blood vessel gurgling in the legs would be a blood clot, which is a deep venous thrombosis, or DVT, in the veins located along the lower legs, thighs and pelvis. What happens is the blood clot ultimately creates a blockage or obstruction in the circulation of blood. This blockage or obstruction will inevitably cause a narrowing within the veins, prompting a gurgling within the area as the blood passes towards the heart. As time goes by, you may begin to experience a certain level of pain or swelling within the affected leg.
While a blood clot can cause blood vessel gurgling, the clot itself rarely forms without some reason or another. Many times, it will be due to some sort of damage to the blood vessels caused by prolonged periods of sitting or bed rest, a recent surgical procedure, a trauma to a bone in the lower leg, thigh or even hip, hormone replacement therapy, use of oral contraceptives, obesity, heart problems or even child birth. The reasons for the damage to the blood vessels that prompt the clot will vary from person to person, but most people will suffer from some of the same symptoms that can indicate the issue is present.
Most people dealing with a blood clot that is causing a "gurgle" with the blood vessel will typically experience some level of pain or swelling, as already mentioned, but may also begin to suffer other symptoms of the condition. This would include a certain amount of discoloration to the skin of the leg, varying from red to blue to white. You may also experience a change in temperature to the leg itself where the area may be warmer to the touch than other areas of the body. You may even begin to suffer from leg cramping and a change in your range of motion, in that you may notice some difficulty in bending the foot of the affected leg. All of these symptoms are a direct result in the change of blood flow, especially from a more persistent condition.
If left untreated, the blood clot could, according to the Mayo Clinic, eventually break off from the area of formation and travel to other areas of the body. Once a blood clot moves into the heart, it could prompt a person to suffer from a heart attack. In the case of the lungs or brain, a blood clot traveling to these areas of the body could result in a pulmonary embolism or a stroke, respectively. If you are suffering from one or more of the symptoms described above, contact your doctor for a check-up. The most effective form of treatment will be early detection.