08 July, 2011
How Green, Leafy Vegetables Affect Coumadin
Your doctor might prescribe Coumadin if you have or are at high risk for developing a blood clot, which could cause a stroke, a lung embolism or deep-vein thrombosis in your limbs. While taking Coumadin, a brand name for the prescription drug warfarin, you must monitor your daily intake of green, leafy vegetables. The vitamin K content in these vegetables could affect how Coumadin works in your body.
The Vitamin K Effect
Your body uses vitamin K to synthesize four of the 13 proteins that your body needs to coagulate, or clot, blood properly. Coumadin works to prevent blood-clot formation by blocking production of these vitamin K-dependent proteins. So if you're using Coumadin and boost your intake of foods rich in vitamin K, that might lower your international normalized ratio, the standard measure of how long it takes blood to clot. A low ratio could raise your risk of developing blood clots.
Vitamin K Content
Some of the richest natural sources of vitamin K are green, leafy vegetables. For example, cooked spinach provides 888 micrograms and cooked Swiss chard supplies 572 micrograms in every cup. Adult men need only 120 micrograms of vitamin K a day; women require about 90 micrograms. One cooked serving of spinach, chard or another green, leafy vegetable, such as leaf lettuce, kale, collard greens or brussels sprouts, far exceeds the average adult's recommended daily allowance.
You still need to consume adequate vitamin K each day, even when you're taking Coumadin, advises the Palo Alto Medical Foundation. You should, however, limit your intake of high-vitamin K foods to one serving a day. You can have up to three servings of foods moderately high in vitamin K -- raw broccoli or spinach and romaine, endive or green leaf lettuce -- each day.
The key to getting the maximum benefit of vitamin K without affecting the function of Coumadin is to eat a consistent amount of the nutrient. Continue to eat the same amount of green, leafy vegetables after you begin taking Coumadin as you did before. Make sure your doctor is aware of your intake so that your dose of the drug can be adjusted accordingly. Do not significantly increase the amount of green, leafy vegetables in your diet without first discussing the change with your doctor.
- Circulation: A Patient's Guide to Taking Coumadin/Warfarin
- Warren Grant Magnusen Clinical Center: Important Information to Know When You Are Taking - Coumadin and Vitamin K
- Harvard School of Public Health: Vitamin K
- USDA National Nutrient Database: Nutrients - Vitamin K (Phylloquinone)
- University of Maryland Medical Center: Vitamin K
- Palo Alto Medical Foundation: Warfarin (Coumadin) and Your Diet
- Szakaly/iStock/Getty Images