L-Glycine Side Effects

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L-glycine, also simply called glycine, is an amino acid your body uses to create proteins and transmit neurochemical signals through your brain. If you suffer from certain medical conditions, such as leg ulcers or schizophrenia, you may benefit from treatment with L-glycine supplements, RxList reports. Talk with your doctor about L-glycine side effects before beginning treatment with this supplement.

Stomach Irritation

You may experience stomach irritation as a side effect of L-glycine. Stomach-related side effects include nausea and vomiting, which may lead to a temporary decrease in your appetite. If stomach irritation persists or becomes severe, seek care from your medical provider.


Intravenous, or IV, administration of L-glycine may induce lightheadedness, Drugs.com cautions. Episodes of lightheadedness may cause you to feel unstable when you attempt to stand or walk about normally. If you experience lightheadedness, sit down or remain seated until this sensation passes. Attempting to move about while you are lightheaded may result in injury from tripping or falling down.

Excessive Salivation

Excessive salivation may occur as a side effect following IV treatment with L-glycine. Increased saliva production may cause you to drool, or you may experience difficult or excessive swallowing. Contact your physician if excessive salivation becomes bothersome.