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Herbal & Vitamins With Klonopin
Klonopin--generic name clonazepam--is a benzodiazepine medication used to treat seizure disorders, anxiety and panic attacks, sleep disorders and muscle spasms. Klonopin has been shown to have adverse interactions with some herbal remedies, and, as always, these should be used with caution. Klonopin may also affect the body's ability to use some vitamins. As always, when using herbal remedies or vitamin supplements, make sure you discuss this with your doctor.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
St. John's Wort
St. John's wort is a popular alternative treatment for anxiety and depression 1. However, its efficacy is still under review. According to the National Center for Complementary and Alternative Medicine, it has been shown to reduce the levels of benzodiazepines in healthy adults 12. It should not be used by people taking Klonopin without the supervision of a physician.
Kava
What Herbs Interact With Paxil?
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Kava is an over-the-counter herbal supplement used to treat anxiety. Kava is believed to increase the effects of benzodiazepines 2. According to Truestar Health, there is limited anecdotal evidence that using kava with benzodiazepines can cause lethargy and disorientation 2.
Kava, like benzodiazepines, causes sedative effects on the brain by working on the GABA receptors 2. While kava use when taking benzodiazepines is not recommended, kava may be a helpful supplement for treating withdrawal symptoms if you are tapering off Klonopin, according to Health Library 2.
Further study is needed to determine a connection between the two. In the meantime, Truestar Health advises that patients should not use kava with any benzodiazepine without medical supervision.
- Kava is an over-the-counter herbal supplement used to treat anxiety.
- In the meantime, Truestar Health advises that patients should not use kava with any benzodiazepine without medical supervision.
Vinpocetine
According to Truestar Health, an extract of the periwinkle plant, vinpocetine, has been shown to cause minor improvements in short-term memory of people taking benzodiazepines 2. Further research is being done. Patients should not take vinpocetine without medical supervision.
Vitamin B9 (Folic Acid)
Valerian & St John's Wort for Anxiety
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According to University of Maryland Medical Center, some benzodiazepines similar to Klonopin may cause a reduction in the levels of folic acid in the blood and may impair the body's ability to use the folic acid it does have 2. Folic acid is particularly important in pregnancy, so make sure you have careful discussions with your obstetrician. Patients may require folic acid supplementation while taking medications in this class. Your physician can test your folic acid levels and recommend supplementation if needed.
- According to University of Maryland Medical Center, some benzodiazepines similar to Klonopin may cause a reduction in the levels of folic acid in the blood and may impair the body's ability to use the folic acid it does have 2.
- Patients may require folic acid supplementation while taking medications in this class.
Vitamin D
Vitamin D is often supplemented in northern climates because the body does not create its own and sunlight is one of the best sources. However, the University of Maryland Medical Center states that anticonvulsant medications, including benzodiazepines, may cause the body to use vitamin D faster 2. Talk to your physician about supplementation.
Biotin (Vitamin H)
While there are no known drug interactions with biotin, some medications used for seizures can reduce the body's supply of biotin, according to the University of Maryland Medical Center. Talk with your physician about supplementation.
Other Possible Interactions
Health Library reports that other herbal supplements that have sedative effects and may increase the impact of benzodiazepines include:
- calendula
- catnip
- hops
- lemon balm
- passionflower
- valerian
- sassafras 2
Related Articles
References
- National Center for Complementary and Alternative Medicine: St. John's Wort and Depression
- Health Library: Benzodiazepines
- U.S. Department of Justice Drug Enforcement Administration. Drugs of abuse, a DEA resource guide. 2017.
- Longo, Lance P., MD and Johnson, Brian, MD. Addiction: part I. benzodiazepines--side effects, abuse risk, and alternatives. American Academy of Family Physicians. 01 Apr 2000. 2121-2131.
- Vinkers CH, Olivier B. Mechanisms underlying tolerance after long-term benzodiazepine use: a future for subtype-selective GABA(A) receptor modulators?. Adv Pharmacol Sci. 2012;2012:416864. doi:10.1155/2012/41686
- Lessenger JE, Feinberg SD. Abuse of prescription and over-the-counter medications. J Am Board Fam Med. 2008;21(1):45-54. doi:10.3122/jabfm.2008.01.070071
- National Institute of Mental Health. Mental health medications. Updated October 2016.
Writer Bio
Susan Landis-Steward has been a print journalist and editor since 1985, writing for "The Reflector," "The Multnomah Village Post," "The Evergreen Messenger" and "The Oregonian." She has won numerous awards for her reporting and has been published in top academic journals. Landis-Steward has a Master of Science in writing from Portland State University.