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At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- National Heart Lung and Blood Institute: Deep Vein Thrombosis, Blood Clots, Venous Thrombosis
- National Heart Lung and Blood Institute: Deep Vein Thrombosis, Blood Clots, Venous Thrombosis
- MayoClinic.com: Deep Vein Thrombosis (DVT): Risk Factors
- Medline Plus Medical Encyclopedia: Blood Clots
- FamilyDoctor.org: Deep Vein Thrombosis
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What Are the Causes of Blood Clots in the Legs?
Blood clots occur when the blood hardens from a liquid to a solid. A blood clot that forms inside a blood vessel and remains there is called a thrombus. A deep vein thrombosis, or DVT, usually occurs in the leg veins 124. Many factors can increase the risk of developing blood clots in the legs, especially if several risk factors occur at the same time.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Vein Damage
According to the National Heart Lung and Blood Institute, a blood clot may form in the legs if damage occurs to the vein's inner lining 1. The damage may result from surgery, serious injury, inflammation or an immune response. Injury or surgery to the veins can slow blood flow, increasing the risk of blood clots.
General anesthetics used during surgery can widen the veins, which increases the risk of blood pooling and then clotting, reports MayoClinic.com.
Slow Blood Flow
Blood clots can form in the legs due to a lack of motion. Inactivity for a long period of time can cause a sluggish or slow blood flow, notes the National Heart Lung and Blood Institute 1. Prolonged sitting, paralysis and recovering in bed after surgery cause the legs to remain still. The blood doesn't circulate in the legs because the calf muscles aren't contracting. Lack of circulation causes blood clots to develop, reports MayoClinic.com.
Pregnancy
A pregnancy, or recently giving birth can cause blood clots to form in the legs, reports FamilyDoctor.org. Pregnancy increases the pressure in the veins of the pelvis and legs. The risk of blood clots from pregnancy can continue for up to six weeks after delivering a baby, reports MayoClinic.com.
Heart Failure
People with heart failure may develop blood clots in the legs because a damaged heart doesn't pump blood as effectively as a normal heart does. The Mayo Clinic advises that inadequate blood flow to the legs increases the chance that blood will pool and clot.
Cancer
According to the Mayo Clinic, some forms of cancer can increase the amount of substances in the blood that cause the blood to clot. Cancer treatment increases the risk of blood clots as well.
Inherited Conditions
MayoClinic.com reports that some inherited conditions may not cause problems unless combined with one or more other risk factors 2.
Other Risk Factors
Other risk factors that cause the blood to clot include taking birth control pills or hormone replacement; a family history of blood clots; smoking; and being overweight or obese, notes the Mayo Clinic.
General anesthetics used during surgery can widen the veins, which increases the risk of blood pooling and then clotting, reports MayoClinic.com. The Mayo Clinic advises that inadequate blood flow to the legs increases the chance that blood will pool and clot. A pregnancy, or recently giving birth can cause blood clots to form in the legs, reports FamilyDoctor.org.
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