How to Block TNF With Herbal Remedies
Tumor necrosis factor, abbreviated as TNF, is a protein that your white blood cells make in response to inflammation or infection throughout your body. Sometimes TNF can be beneficial to your body by heightening your immune response. TNF can also be harmful, as the substance might activate other bodily reactions, such as the growth of cancer cells, according to Breast Cancer Choices. Certain herbal remedies may help block TNF, which might improve your health.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Cook with turmeric to block TNF. Turmeric is an herb commonly used in curries and other Indian dishes and is available in the spice aisle of most supermarkets. Turmeric contains a chemical called curcumin, which is traditionally used to control inflammation. The spice may also play a role in inhibiting TNF, according to the Multiple Sclerosis Encyclopaedia 4. Curcumin is also available in capsule form if you do not like the taste of turmeric.
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Take milk thistle to inhibit TNF. Milk thistle is a plant used mainly to protect against and treat liver disease. Silymarin, a main component of milk thistle, has antioxidant and anti-flammatory properties. A 1999 article in the Journal of Immunology reports that these properties can also block TNF from activating a nuclear transcription factor in the body that controls inflammation and the development of cancer cells. The University of Maryland Medical Center recommends 280 to 450 mg of milk thistle daily for adults 2.
Ask your doctor about taking stinging nettle leaf extract to inihibit TNF. This herbal remedy's effect on colitis, a chronic inflammatory disease, was investigated by German and Swiss researchers. The results, reported in the January 2005 issue of the International Journal of Colorectal Disease, showed that concentrations of TNF were lower in animals who were given nettle leaf extract than those who were not treated with herbal remedies. Stinging nettle leaves can be brewed into a a tea or taken as a fluid extract.
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- "The Journal of Immunology"; ilymarin Suppresses TNF-Induced Activation of NF-B, c-Jun N-Terminal Kinase, and Apoptosis; Sunil K. Manna et al; 1999.
- University of Maryland Medical Center: Milk Thistle
- BreastCancer.org: Supplement Strategies: Curcumin
- Multiple Sclerosis Encyclopaedia: Curcumin
- National Center for Complementary and Integrative Health. Milk Thistle. Updated September 2016.
- Abenavoli L, Capasso R, Milic N, Capasso F. Milk thistle in liver diseases: past, present, future. Phytother Res. 2010;24(10):1423-32. doi:10.1002/ptr.3207
- Salmi HA, Sarna S. Effect of silymarin on chemical, functional, and morphological alterations of the liver. A double-blind controlled study. Scand J Gastroenterol. 1982;17(4):517-21. doi:10.3109/00365528209182242
- Seeff LB, Curto TM, Szabo G, et al. Herbal product use by persons enrolled in the hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. Hepatology. 2008;47(2):605-12. doi:10.1002/hep.22044
- Fried MW, Navarro VJ, Afdhal N, et al. Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. JAMA. 2012;308(3):274-82. doi:10.1001/jama.2012.8265
- Ebrahimpour koujan S, Gargari BP, Mobasseri M, Valizadeh H, Asghari-jafarabadi M. Effects of Silybum marianum (L.) Gaertn. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. Phytomedicine. 2015;22(2):290-6. doi:10.1016/j.phymed.2014.12.010
- Kazazis CE, Evangelopoulos AA, Kollas A, Vallianou NG. The therapeutic potential of milk thistle in diabetes. Rev Diabet Stud. 2014;11(2):167-74. doi:10.1900/RDS.2014.11.167
- Ebrahimpour, K.; Gargari, B.; Mobasseri, M. et al. Effects of Silybum marianum (L.) Gaertn. (silymarin) extract supplementation on antioxidant status and hs-CRP in patients with type 2 diabetes mellitus: a randomized, triple-blind, placebo-controlled clinical trial. Phytomedicine. 2015 Feb 15;22(2):290-6. DOI: 10.1016/j.phymed.2014.12.010.
- Fried, M.; Navarro, V.; Afdhal, N. et al. Effect of silymarin (milk thistle) on liver disease in patients with chronic hepatitis C unsuccessfully treated with interferon therapy: a randomized controlled trial. JAMA. 2012 Jul 18;308(3):274-82. DOI: 10.1001/jama.2012.8265.
- Rambaldi, A.; Jacobs, B.; Iaquinto G, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C liver diseases--a systematic Cochrane hepato-biliary group review with meta-analyses of randomized clinical trials. Am J Gastroenterol. 2005 Nov;100(11):2583-91. DOI: 10.1111/j.1572-0241.2005.00262.x.
- Salmi, H. and Sarna, S. Effect of silymarin on chemical, functional, and morphological alterations of the liver. A double-blind controlled study. Scan J Gastroenterol. 1982;17:517–21.
- Seeff, L.; Curto, T.; Szabo, G. et al. Herbal product use by persons enrolled in the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis (HALT-C) Trial. Hepatology. 2008;47(2):605-12. DOI: 10.1002/hep.22044.
- Voroneanu, L.; Nistor, I.; Dumea, R. et al. Silymarin in Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. J Diabetes Res. 2016;2016:5147468. DOI: 10.1155/2016/5147468.
Erica Roth has been a writer since 2007. She is a member of the Society of Professional Journalists and was a college reference librarian for eight years. Roth earned a Bachelor of Arts in French literature from Brandeis University and Master of Library Science from Simmons College Graduate School of Library and Information Science. Her articles appear on various websites.