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At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- The New England Journal of Medicine: Association Between Body Mass Index and Gastroesophageal Reflux Symptoms in Both Normal Weight and Overweight Women
- The New England Journal of Medicine: Association Between Body Mass Index and Gastroesophageal Reflux Symptoms in Both Normal Weight and Overweight Women
- Gastroenterology and Hepatology: Pill-Induced Esophagitis
- Gastroenterology and Hepatology: Pill-Induced Esophagitis
- Canadian Journal of Gastroenterology: Canadian Digestive Health Foundation Public Impact Series: Gastroesophageal Reflux Disease in Canada -- Incidence, Prevalence, and Direct and Indirect Economic Impact
- Canadian Journal of Gastroenterology: Canadian Digestive Health Foundation Public Impact Series: Gastroesophageal Reflux Disease in Canada -- Incidence, Prevalence, and Direct and Indirect Economic Impact
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
What Causes Heartburn in Women?
Heartburn occurs when stomach acid backs up into the esophagus -- the muscular tube that allows food to travel from the mouth to the stomach. According to the American College of Gastroenterology, more than 60 million people experience heartburn, also called acid reflux, at least once per month. Symptoms of acid reflux vary, but typically include a burning sensation in the chest. While anyone can experience heartburn, several factors specifically increase women's risk of the condition.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Hormones
Hormonal shifts in women may provoke heartburn episodes. Hormones can cause relaxation of the valve at the lower end of the esophagus that usually keeps digestive acids in the stomach, allowing acid reflux to occur. Fluctuations in estrogen can play a role, but the hormone progesterone is also known to trigger heartburn. Progesterone levels increase dramatically during pregnancy, which is one reason why pregnant women often experience morning sickness and heartburn. Likewise, birth control pills containing estrogen or progesterone can cause heartburn.
- Hormonal shifts in women may provoke heartburn episodes.
- Progesterone levels increase dramatically during pregnancy, which is one reason why pregnant women often experience morning sickness and heartburn.
Weight Gain
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Weight gain is another risk factor for heartburn. Excess abdominal weight puts added pressure on the stomach, which can encourage acid to back up into the esophagus. A June 2006 study published in "The New England Journal of Medicine" found that, of more than 10,000 women participants, those who were overweight and obese were two to three times more likely than normal weight women to experience acid reflux symptoms 2. The researchers noted that even modest weight loss can help improve the intensity and frequency of heartburn episodes.
- Weight gain is another risk factor for heartburn.
- The researchers noted that even modest weight loss can help improve the intensity and frequency of heartburn episodes.
Medications
In some cases, certain medications can irritate the esophagus and trigger heartburn symptoms. Women are apt to take several medications that have been linked to esophageal irritation, including antibiotics for urinary tract infections and nonsteroidal anti-inflammatory medications, such as:
- aspirin
- ibuprofen (Advil
- Motrin)
- naproxen (Aleve
- Naprosyn)
Bisphosphonate drugs used to prevent and treat osteoporosis can also cause esophageal symptoms. Common offenders include alendronate (Fosamax, Binosto), risedronate (Actonel, Atelvia) and ibandronate (Boniva). Taking medications exactly as prescribed helps prevent acid reflux. In particular, avoiding lying down for a period of time after taking pills can reduce the likelihood of heartburn.
- In some cases, certain medications can irritate the esophagus and trigger heartburn symptoms.
- Women are apt to take several medications that have been linked to esophageal irritation, including antibiotics for urinary tract infections and nonsteroidal anti-inflammatory medications, such as: * aspirin
* ibuprofen (Advil
* Motrin)
* naproxen (Aleve
* Naprosyn) Bisphosphonate drugs used to prevent and treat osteoporosis can also cause esophageal symptoms.
Lifestyle Habits
Can You Eat Anything to Get Rid of Heartburn?
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A number of lifestyle choices make some women more prone to heartburn than others. Frequent consumption of caffeinated beverages, including coffee and tea, can trigger heartburn. Eating high-fat meals directly before bedtime increases the risk of acid reflux as well. Additionally, smoking and heavy drinking have been associated with heartburn. Keep in mind that for women, one alcoholic beverage per day is considered drinking in moderation.
- A number of lifestyle choices make some women more prone to heartburn than others.
- Additionally, smoking and heavy drinking have been associated with heartburn.
Related Articles
References
- Canadian Family Physician: Treatment of Heartburn and Acid Reflux Associated with Nausea and Vomiting during Pregnancy
- The New England Journal of Medicine: Association Between Body Mass Index and Gastroesophageal Reflux Symptoms in Both Normal Weight and Overweight Women
- Gastroenterology and Hepatology: Pill-Induced Esophagitis
- Canadian Journal of Gastroenterology: Canadian Digestive Health Foundation Public Impact Series: Gastroesophageal Reflux Disease in Canada -- Incidence, Prevalence, and Direct and Indirect Economic Impact
- Johns Hopkins Medicine. 10 tips to prevent reflux disease. 2013.
- Harvard Medical School. Gastroesophageal reflux: More than just heartburn. 2014.
- Harvard Medical School. Take control of your heartburn.
- Monajemzadeh M, Haghi-ashtiani MT, Soleymani R, et al. Is there any association between passive smoking and esophagitis in pediatrics?. Iran J Pediatr. 2013;23(2):194-8.
- TeensHealth from Nemours. Gastroesophageal reflux disease (GERD). Updated January, 2015.
- Cleveland Clinic. GERD (chronic acid reflux): Prevention. Updated December 6, 2019.
- Harvard Medical School. 11 stomach-soothing steps for heartburn.
- American Society for Gastrointestinal Endoscopy. Diet and gastroesophageal reflux disease (GERD). 2014.
- Harvard Medical School. What to eat when you have chronic heartburn. Updated October 22, 2019.
- Liszt KI, Ley JP, Lieder B, et al. Caffeine induces gastric acid secretion via bitter taste signaling in gastric parietal cells. Proc Natl Acad Sci USA. 2017;114(30):E6260-E6269. doi:0.1073/pnas.1703728114
- Chen SH, Wang JW, Li YM. Is alcohol consumption associated with gastroesophageal reflux disease?. J Zhejiang Univ Sci B. 2010;11(6):423-8. doi:10.1631/jzus.B1000013
- Singh M, Lee J, Gupta N, et al. Weight loss can lead to resolution of gastroesophageal reflux disease symptoms: a prospective intervention trial. Obesity (Silver Spring). 2013;21(2):284-90.
- National Institute of Diabetes Digestive and Kidney Diseases. Symptoms & causes of GER & GERD. Updated November 2014.
- Harvard Medical School. 8 ways to quell the fire of heartburn.
- Mendes-filho AM, Moraes-filho JP, Nasi A, et al. Influence of exercise testing in gastroesophageal reflux in patients with gastroesophageal reflux disease. Arq Bras Cir Dig. 2014;27(1):3-8. doi:10.1590/S0102-67202014000100002
- Cleveland Clinic. Why does your heartburn always seem worse at night?. August 17, 2017.
- Cleveland Clinic. GERD (chronic acid reflux). Updated December 6, 2019.
- Allampati S, Lopez R, Thota PN, Ray M, Birgisson S, Gabbard SL. Use of a positional therapy device significantly improves nocturnal gastroesophageal reflux symptoms. Diseases of the Esophagus. 2016. doi:10.1111/dote.12495.
- Ness-Jensen E, Hveem K, El-Serag H, Lagergren J. Lifestyle intervention in gastroesophageal reflux disease. Clinical Gastroenterology and Hepatology : The Official Clinical Practice Journal of the American Gastroenterological Association. 2016;14(2):175-182.e3. doi:10.1016/j.cgh.2015.04.176
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Writer Bio
Niya Jones is a physician and medical writer. She is board-certified in internal medicine and has a special interest in cardiology, particularly as it relates to health care disparities and women's health. She received her medical degree and Masters of public health from Yale University.