What Are the Side Effects of Natrilix SR?

Natrilix SR is a diuretic that works to reduce high blood pressure, known as hypertension. High blood pressure occurs when blood pushes against the artery walls hard enough to result in medical problems such as heart disease. Diuretics, or water pills, lower blood pressure by eliminating sodium and water from blood volume. This reduced volume provides less fluid in the arteries, so stress against the walls subsides. Natrilix SR is a film-coated tablet that releases the drug over a long period of time. The pill is taken once daily in the morning, according to the drug leaflet, provided by Medicines.org.uk.

Is This an Emergency?

If you are experiencing serious medical symptoms, seek emergency treatment immediately.


Medicines.org.uk reports a few patients—one in 1,000—will feel dizzy and nauseous when taking Natrilix SR. A general feeling of malaise may be a side effect of this medication due to dehydration. Additionally, patients may be constipated, have dry mouth and feel tired. The methodology of the medication reduces water in the body. To combat these side effects, talk to your doctor about increasing your daily fluid intake. Some high risk groups, such as the elderly, may experience dehydration serious enough to cause heart failure.

Allergic Reaction

With any medication, including Natrilix SR, there is a risk of allergic reaction. Vomiting, swelling in the throat, tongue inflammation, a skin rash known as purpura or other dermatological problems such as itching can indicate a reaction to one or more of the ingredients in the drug. When a person has an allergic response to medication, the immune system determines incorrectly that the drug is a harmful substance. Similar symptoms may occur during an adverse drug event. This is a physical reaction to a drug that has nothing to do with the immune system. Betterhealth,vic.gov.au states that the most common indications of an allergy or adverse drug event may be rash, hives or fever. A true allergic reaction may be life-threatening. If you feel any side effects after taking Natrillix SR, especially shortness of breath or swelling in the throat, seek medical help immediately.

Muscle Weakness

According to Medicines.org.uk, the most common side effect from taking Natrilix SR is muscle weakness. This is due to a low potassium level in the blood. Muscles require potassium to function. The diuretic effect of the drug will reduce the potassium and weaken muscles. If the muscle weakness is severe enough to affect your life, talk to your doctor about trying a different medication to treat your high blood pressure.