Multiple myeloma and myeloid leukemia have much in common 24. The names are similar, because they are both cancers that start in the bone marrow. Many of the symptoms are similar, and even some of the same drugs are used to treat both diseases. However, they are two distinctly different entities.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Multiple myeloma and myeloid leukemia involve different cell types 24. Multiple myeloma involve a type of B cell called a plasma cell 2. The name "myeloma" is somewhat deceiving because this cancer does not involve myeloid cells. It gets its name because it arises in the myelium, or bone marrow. The National Cancer Institute explains that myleloid leukemia arises in myeloblasts, which are derived from the myeloid line of cells 1. These cells also arise in the bone marrow, but they are not plasma cells.
Reasons for Elevated WBC
Although patients with multiple myeloma and myeloid leukemia both suffer from anemia, bruising and infections, MayoClinic.com explains that patients with multiple myeloma suffer bone fractures in parts of the bone where the cancer is lodged 24. The Leukemia and Lymphoma Society expands on this saying that 90 percent of patients have cancer lodged in different bony locations, which is why it is referred to as "multiple. 4"
To further complicate matters, some patients with multiple myeloma later get a type of myeloid leukemia called acute myeloid leukemia, or AML 2. In 2006, a group from New York University Medical Center published a paper in the "Archives of Pathology and Laboratory Medicine" describing a 81-year-old man who presented with AML four years after being successfully treated for multiple myeloma 2. The scientific literature is rife with specific examples of this.
Reasons for Elevated WBC
8 Types of Lymphoma Cancer
White Blood Cells & Their Functions
Causes of High MPV Blood
Signs & Symptoms of Uterine Fibroids Vs. Ovarian Cancer
Symptoms of Cecum Carcinoma
Common Cell Diseases
Five Stages of Cancer
What Is a Bone Lesion?
Stage 3 Cancer Life Expectancy
- National Cancer Institute: General Information About Adult Acute Myeloid Leukemia
- MayoClinic.com: Multiple Myeloma
- National Cancer Institute: What You Need to Know about Multiple Myeloma
- Leukemia and Lymphoma Society: Myeloma
- American Cancer Society. Can Multiple Myeloma Be Found Early?
- American Cancer Society. Tests to Find Multiple Myeloma
- American Cancer Society. What Is Multiple Myeloma?
- González-calle V, Slack A, Keane N, et al. Evaluation of Revised International Staging System (R-ISS) for transplant-eligible multiple myeloma patients. Ann Hematol. 2018;97(8):1453-1462. doi:10.1007/s00277-018-3316-7
- mSMART 3.0: Classification of Active MM.
- Rajkumar SV, Dimopoulos MA, Palumbo A, et al. International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncol. 2014;15(12):e538-548. doi:10.1016/S1470-2045(14)70442-5
- Rajkumar SV, Kumar S. Multiple myeloma: diagnosis and treatment. Mayo Clin Proc. 2016;91(1):101-119. doi:10.1016/j.mayocp.2015.11.007
Shelly Morgan has been writing and editing for over 25 years for various medical and scientific publications. Although she began her professional career in pharmacological research, Morgan turned to patent law where she specialized in prosecuting patents for medical devices. She also writes about renal disease and hypertension for several nonprofits aimed at educating and supporting kidney patients.