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At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- "Urology"; Effect of a Lipidic Extract from Lepidum Meyenii on Sexual Behavior in Mice and Rats; B. Zheng et al.
- "Urology"; Effect of a Lipidic Extract from Lepidum Meyenii on Sexual Behavior in Mice and Rats; B. Zheng et al.
- "CNS Neuroscience and Therapeutics"; A Double-Blind, Randomized, Pilot Dose-Finding Study of Maca Root for the Management of SSRI-induced Sexual Dysfunction; C. Dording et al.
- "CNS Neuroscience and Therapeutics"; A Double-Blind, Randomized, Pilot Dose-Finding Study of Maca Root for the Management of SSRI-induced Sexual Dysfunction; C. Dording et al.
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
The Side Effects of SSRIs & Maca Root
Selective serotonin reuptake inhibitors, or SSRIs, are medications often prescribed to relieve symptoms of depression. Although there are several drugs in this category, all can have similar side effects, which can include nausea, headache, agitation and insomnia. SSRIs may also cause decreased libido in some people, as well as problems maintaining an erection for men and difficulty experiencing an orgasm for both sexes. Maca is a traditional herbal remedy that may relieve some of the sexual side effects of SSRIs. Consult your doctor to determine if taking maca is appropriate for you.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
SSRIs
Serotonin is a neurotransmitter produced in several parts of your brain. It modifies some important functions, such as mood, sleep patterns and appetite. SSRIs inhibit the reabsorption of serotonin by nerve cells, making the neurotransmitter remain in the junction between the nerves cells -- the synapse -- for a longer time. The result is often an improvement in mood. Because they are considered effective drugs, patients often put up with the sexual side effects that SSRIs can cause. Maca is a natural treatment that may decrease some of these effects, increasing libido and improving sexual function.
- Serotonin is a neurotransmitter produced in several parts of your brain.
- Because they are considered effective drugs, patients often put up with the sexual side effects that SSRIs can cause.
Maca
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Maca, or Lepidium meyenii, is a native South American plant that grows at high elevations and belongs to the same family as broccoli and cabbage. South Americans have used maca root for hundreds of years as a remedy for several sexual complaints including infertility, symptoms of menopause and poor libido and sexual performance. The root contains several natural compounds that may be responsible for aiding in the relief of some sexual problems. Although its mechanism is not well understood, it does not involve changes in any of the sex hormones, according to the Memorial Sloan-Kettering Cancer Center website 1.
- Maca, or Lepidium meyenii, is a native South American plant that grows at high elevations and belongs to the same family as broccoli and cabbage.
- South Americans have used maca root for hundreds of years as a remedy for several sexual complaints including infertility, symptoms of menopause and poor libido and sexual performance.
Maca Research
A number of laboratory and clinical studies have examined the potential for maca to improve sexual performance. For example, in a study published in "Urology" in April 2000, laboratory animals that consumed maca extract had enhanced sexual function compared to another group given a placebo. In a clinical trial published in "CNS Neuroscience and Therapeutics" in August 2008, human subjects with SSRI-induced sexual problems consumed either maca or a placebo 4. In this study, taking maca resulted in significant improvement in both sexual function and libido.
- A number of laboratory and clinical studies have examined the potential for maca to improve sexual performance.
- In this study, taking maca resulted in significant improvement in both sexual function and libido.
Recommendations and Precautions
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Maca is available from most health food stores in capsules or tablets. The usual dose is 450 milligrams, three times daily. Maca is generally considered safe and typically does not have any significant side effects. However, do not take maca if you are pregnant or breastfeeding since its safety in these situations has not been tested. Discuss the use of maca with your healthcare provider to be certain that it is a good choice for you.
- Maca is available from most health food stores in capsules or tablets.
- However, do not take maca if you are pregnant or breastfeeding since its safety in these situations has not been tested.
Related Articles
References
- Memorial Sloan-Kettering Cancer Center: Maca
- "Urology"; Effect of a Lipidic Extract from Lepidum Meyenii on Sexual Behavior in Mice and Rats; B. Zheng et al.
- "CNS Neuroscience and Therapeutics"; A Double-Blind, Randomized, Pilot Dose-Finding Study of Maca Root for the Management of SSRI-induced Sexual Dysfunction; C. Dording et al.
- Drugs.com: Maca
- Ley, BM. Maca! Adaptogen and Hormonal Regulator. Minneapolis, MN: BL Publications: 2003.
- Shin BC, Lee MS, Yang EJ, Lim HS, Ernst E. Maca (L. meyenii) for improving sexual function: a systematic review. BMC Complement Altern Med. 2010;10:44. doi:10.1186/1472-6882-10-44
- Gonzales GF, Córdova A, Vega K, et al. Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men. Andrologia. 2002;34(6):367-72. doi:10.1046/j.1439-0272.2002.00519.x
- Dording CM, Schettler PJ, Dalton ED, et al. A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evid Based Complement Alternat Med. 2015;2015:949036. doi:10.1155/2015/949036
- Melnikovova I, Fait T, Kolarova M, Fernandez EC, Milella L. Effect of Lepidium meyenii Walp. on semen parameters and serum hormone levels in healthy adult men: a double-blind, randomized, placebo-controlled pilot study. Evid Based Complement Alternat Med. 2015;2015:324369. doi:10.1155/2015/324369
- Stojanovska L, Law C, Lai B, et al. Maca reduces blood pressure and depression, in a pilot study in postmenopausal women. Climacteric. 2015;18(1):69-78. doi:10.3109/13697137.2014.929649
- Oshima M, Gu Y, Tsukada S. Effects of Lepidium meyenii Walp and Jatropha macrantha on blood levels of estradiol-17 beta, progesterone, testosterone and the rate of embryo implantation in mice. J Vet Med Sci. 2003;65(10):1145-6. doi:10.1292/jvms.65.1145
- Loria, K. How to choose supplements wisely. Consumer Reports. Updated October 30, 2019.
- Dording CM, Schettler PJ, Dalton ED, et al. A double-blind placebo-controlled trial of maca root as treatment for antidepressant-induced sexual dysfunction in women. Evid Based Complement Alternat Med. 2015;2015:949036. doi: 10.1155/2015/949036
- Gonzales GF, Córdova A, Vega K, et al. Effect of Lepidium meyenii (MACA) on sexual desire and its absent relationship with serum testosterone levels in adult healthy men. Andrologia. 2002;34(6):367-72.
- Melnikovova I, Fait T, Kolarova M, Fernandez EC, Milella L. Effect of Lepidium meyenii Walp. on Semen Parameters and Serum Hormone Levels in Healthy Adult Men: A Double-Blind, Randomized, Placebo-Controlled Pilot Study. Evid Based Complement Alternat Med. 2015;2015:324369. doi: 10.1155/2015/324369
- Shin BC, Lee MS, Yang EJ, et al. Maca (L. meyenii) for improving sexual function: a systematic review. BMC Complement Altern Med. 2010;10:44. doi: 10.1186/1472-6882-10-44.
- Stojanovska L, Law C, Lai B, et al. Maca Reduces Blood Pressure and Depression, in a Pilot Study in Postmenopausal Women. Climacteric. 2015;18(1):69-78. doi: 10.3109/13697137.2014.929649
Writer Bio
Joanne Marie began writing professionally in 1981. Her work has appeared in health, medical and scientific publications such as Endocrinology and Journal of Cell Biology. She has also published in hobbyist offerings such as The Hobstarand The Bagpiper. Marie is a certified master gardener and has a Ph.D. in anatomy from Temple University School of Medicine.