The Side Effects of Co-Codamol Tablets

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Co-codamol is a prescription medication that employs both paracetamol and codeine phosphate as its main ingredients. It is most widely used as a pain reliever and fever reducer. Some adverse side effects may be experienced while using this medication. A doctor should be consulted before taking pain relievers such as co-codamol.


The two major active ingredients in co-codamol are paracetamol and codeine phosphate. According to, “Paracetamol is used in the treatment of mild to moderate pain, and for reducing fever. Codeine is an opioid, which mimics the effect of endorphins, which are naturally occurring pain-reducing chemicals, and helps program them to relieve your pain.”

Common Side Effects

As with any medication, some side effects have been associated with the use of co-codamol. Some common side effects that may be experienced include, but are not limited to, dizziness, light-headedness, nausea or vomiting, sleepiness, vision disturbance, tiredness or weakness, constipation, insomnia, painful urination, stomach cramps, constipation, painful urination, nightmares, dry mouth, a false sense of well-being, headache or malaise.

Rare Side Effects

There are other, more rare and serious side effects associated with the use of co-codamol. Some rare side effects include, but are not limited to, dark urine, black, bloody or tarry stool, sore throat, white spots on the mouth or lips, pain in the lower back or side, irregular heartbeat, jaundice, restlessness, tremors, irregular breathing, sweating, facial swelling, flushing, ringing in the ears, depression, mood swings, pale stool or hallucinations.


More than two tablets of co-codamol should never be taken at one time. Taking more than the recommended dose of this medication can greatly increase the likelihood of experiencing side effects or even an overdose. Signs of an overdose include clammy skin, confusion, severe weakness, slow heartbeat, pinpoint pupils, severe drowsiness, liver or kidney damage, low blood pressure and severe nervousness or restlessness.


Some medical conditions can affect co-codamol use. A doctor should be consulted before taking this medication if a person has a history of alcoholic liver disease, drug addiction, emotional problems, brain diseases, lung diseases such as emphysema, asthma, enlarged prostate, epilepsy, low blood pressure, heart disease, gallstones, kidney or liver disease. Chances of experiencing serious side effects are increased in people with underactive thyroids. Withdrawal symptoms such as sweating, nausea, severe fatigue, runny nose, pain, vomiting and depression may be experienced if use of this medication is stopped suddenly.