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- Mayo Clinic: Keratosis Pilaris: Home and Lifestyle
- Mayo Clinic: Kertosis Pilaris: Treatment and Drugs
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How to Reduce Keratin Production
Increased keratin production is responsible for a condition called keratosis pilaris. Keratosis pilaris symptoms include hardened dry bumps that have a yellow hue at the surface of the skin. The yellow hue is a result of keratin that has hardened under the skin's surface to form a plug. Removing the plug or exfoliating may worsen this condition, as it is not a bacterial infection, such as with acne. In order to decrease keratin production, it is important to follow your dermatologist's instructions carefully and use all medications as directed.
Apply lactic-acid containing products to the keratin overproduction site twice daily. According to the Mayo Clinic, lactic acid softens and inhibits overproduction of keratin in the skin. Lactic-acid based moisturizers and creams are available over the counter at your local pharmacy or beauty supply store.
How to Reduce Keratin
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Moisturize the skin daily after bathing. Moisturizers containing urea, glycolic acid, salicylic acid, tretinoin or vitamin D may be recommended by your dermatologist, according to the University of Maryland Medical Center. Daily moisturizing may take several months to improve the condition and symptoms may return should you discontinue use.
Apply cortisteroid creams as directed by your dermatologist. These are prescription anti-inflammatory creams that reduce keratin cell turnover and decrease inflammation of the skin. According to the Mayo Clinic, cortisteroids are for short-term use only as longer-term use can aggravate the skin, causing excessive dryness and other irritations.
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Opt for a prescription topical retinoid. Retinoids are derived from vitamin A complex and help prevent clogging of follicles. According to the Mayo Clinic, retinoids may be an effective treatment, but skin dryness and irritation may occur in individuals with sensitive skin 2.
Run a humidifier in your home throughout the day. This keeps moisture in the air, preventing your skin from drying out and overproduction of keratin within the skin. The Mayo Clinic suggests using a portable humidifier that can be attached to your home furnace. This allows for even moisture distribution throughout the entire home instead of just one room.
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References
- Mayo Clinic: Keratosis Pilaris: Home and Lifestyle
- Mayo Clinic: Kertosis Pilaris: Treatment and Drugs
- Bragulla HH, Homberger DG. Structure and functions of keratin proteins in simple, stratified, keratinized and cornified epithelia. J Anat. 2009;214(4):516-59. doi:10.1111/j.1469-7580.2009.01066.x
- Jacob JT, Coulombe PA, Kwan R, Omary MB. Types I and II keratin intermediate filaments. Cold Spring Harb Perspect Biol. 2018;10(4):a018275. doi:10.1101/cshperspect.a018275
- Moll R, Divo M, Langbein L. The human keratins: biology and pathology. Histochem Cell Biol. 2008;129(6):705-33. doi:10.1007/s00418-008-0435-6
- Greenwold MJ, Bao W, Jarvis ED, Hu H, Li C, Gilbert MT, Zhang G, Sawyer RH. Dynamic evolution of the alpha (α) and beta (β) keratins has accompanied integument diversification and the adaptation of birds into novel lifestyles. BMC Evol Biol. 2014;14:249. doi:10.1186/s12862-014-0249-1
- Hassan MM, Carr CM. A review of the sustainable methods in imparting shrink resistance to wool fabrics. J Adv Res. 2019;18:39-60. doi:10.1016/j.jare.2019.01.014
- Thomas M, Khopkar US. Keratosis pilaris revisited: Is it more than just a follicular keratosis?. Int J Trichology. 2012;4(4):255-8. doi:10.4103/0974-7753.111215
- American Academy of Dermatology. Actinic keratosis: Overview.
- MedlinePlus. Epidermolytic hyperkeratosis.
- Madke B, Gutte R, Doshi B, Khopkar U. Hyperkeratotic palmoplantar lichen planus in a child. Indian J Dermatol. 2013;58(5):405. doi:10.4103/0019-5154
- Basit A, Asghar F, Sadaf S, Akhtar MW. Health improvement of human hair and their reshaping using recombinant keratin K31. Biotechnol Rep (Amst). 2018;20:e00288. doi:10.1016/j.btre.2018.e00288
- Patel DP, Swink SM, Castelo-Soccio L. A review of the use of biotin for hair loss. Skin Appendage Disord. 2017;3(3):166-169. doi:10.1159/000462981
- Crum EM, McLeay YD, Barnes MJ, Stannard SR. The effect of chronic soluble keratin supplementation in physically active individuals on body composition, blood parameters and cycling performance. J Int Soc Sports Nutr. 2018;15(1):47. doi:10.1186/s12970-018-0251-x
- Pierce JS, Abelmann A, Spicer LJ, Adams RE, Glynn ME, Neier K, Finley BL, Gaffney SH. Characterization of formaldehyde exposure resulting from the use of four professional hair straightening products. J Occup Environ Hyg. 2011;8(11):686-99. doi:10.1080/15459624.2011.626259
- Swenberg JA, Moeller BC, Lu K, Rager JE, Fry RC, Starr TB. Formaldehyde carcinogenicity research: 30 years and counting for mode of action, epidemiology, and cancer risk assessment. Toxicol Pathol. 2013;41(2):181-9. doi:10.1177/0192623312466459
Writer Bio
Sharin Griffin has been a freelance writer since 2009, specializing in health-related articles. She has worked in the health-care industry as a certified nursing assistant and medical technician. Griffin's medical expertise encompasses bariatrics and geriatric care, with an emphasis on general medicine. She is completing an associate degree in health-care administration from Axia University.