High Testosterone & Pregnancy
Though testosterone is the dominant male hormone, women have some as well. Women who have high levels of testosterone, however, often have difficulty getting pregnant and carrying a pregnancy full-term. **Complications may also arise during pregnancy if you have high testosterone levels 2. If you suspect you have a high level of testosterone, consult an endocrinologist for diagnosis and treatment.
Causes
One of the most common causes of high testosterone levels in women in polycystic ovary syndrome, more commonly known as PCOS 1. Because PCOS interferes with ovulation, this disorder is one of the most common causes of infertility, according to the National Institutes of Health 1.
Fertility Effects
Hormones to Help Get Pregnant
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Many women with high androgen levels don’t ovulate. If you don’t produce a mature egg and ovulate, you can’t get pregnant. Medications to lower testosterone, such as certain birth control pills or medications such as metformin, which improves insulin resistance, the cause of many PCOS symptoms, may induce ovulation. You may need more potent fertility medications such as Clomid or injectable medications called gonadotropins. ; June 2004'). All these factors make getting pregnant difficult.
- Many women with high androgen levels don’t ovulate.
Miscarriage Rates
Women with high testosterone levels also have a higher risk of miscarriage once they do get pregnant. December 2000'). Researchers from the Sheffield Teaching Hospitals also found high androgen levels in 11 percent of women with recurrent miscarriage, according to a February 2008 article published in “Human Reproduction. 4”
- Women with high testosterone levels also have a higher risk of miscarriage once they do get pregnant.
Pregnancy Complications
Wheat Germ & Fertility
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; August 2006').
Related Articles
References
- "European Journal of Endocrinology"; Maternal Testosterone Levels During Pregnancy are Associated with Offspring Size at Birth; S. Carlsen, et al.; August 2006
- "Diabetologia Croatica"; Effect Increased Testosterone Level on Women's Fertility; Z. Seranda, et al.; June 2004
- "Human Reproduction"; Does Free Androgen Index Predict Subsequent Pregnancy Outcome in Women with Recurrent Miscarriage?; K.A. Cocksedge, et al.; February 2008
- University of Rochester Medical Center. Total testosterone. 2019.
- MedlinePlus. Testosterone injection. Updated March 15, 2019.
- MedlinePlus. Testosterone levels test. Reviewed June 27, 2018.
- Long N, Nguyen L, Stevermer J. PURLS: It's time to reconsider early-morning testosterone tests. J Fam Pract. 2015;64(7):418-9.
- Kaiser Permanente. Testosterone results. Updated November 6, 2018.
- American Society for Reproductive Medicine. Testosterone use and male fertility. 2015.
- Harvard Health Publishing. Testosterone - what it does and doesn't do. Updated August 29, 2019.
- Franks S, Hardy K. Androgen action in the ovary. Front Endocrinol (Lausanne). 2018;9:452. doi:10.3389/fendo.2018.00452
- Test ID: TGRP; Testosterone, Total and Free, Serum. MayoClinic Medical Laboratories.
- Testosterone: Drug information. Lexicomp, Inc. UptoDate.com.
- Camacho EM, Huhtaniemi IT, O'Neill TW, et al. Age-associated changes in hypothalamic-pituitary-testicular function in middle-aged and older men are modified by weight change and lifestyle factors: longitudinal results from the European Male Ageing Study. Eur J Endocrinol. 2013;168(3):445-55. doi:10.1530/EJE-12-0890
- Kolettis PN, Purcell ML, Parker W, Poston T, Nangia AK. Medical testosterone: an iatrogenic cause of male infertility and a growing problem. Urology. May;85(5):1068-72. doi:10.1016/j.urology.2014.12.052
- Samplaski MK, Loai Y, Wong K, Lo KC, Grober ED, Jarvi KA. Testosterone use in the male infertility population: prescribing patterns and effects on semen and hormonal parameters. Fertil Steril. 2014;101(1):64-9. doi:10.1016/j.fertnstert.2013.09.003
- Spritzer MD, Daviau ED, Coneeny MK, Engelman SM, Prince WT, Rodriguez-Wisdom KN. Effects of testosterone on spatial learning and memory in adult male rats. Horm Behav. 2011;59(4):484-96. doi:10.1016/j.yhbeh.2011.01.009
- van Honk J, Schutter DJ, Bos PA, Kruijt AW, Lentjes EG, Baron-Cohen S. Testosterone administration impairs cognitive empathy in women depending on second-to-fourth digit ratio. Proc Natl Acad Sci U S A. 2011;108(8):3448-52. doi:10.1073/pnas.1011891108
Writer Bio
A registered nurse with more than 25 years of experience in oncology, labor/delivery, neonatal intensive care, infertility and ophthalmology, Sharon Perkins has also coauthored and edited numerous health books for the Wiley "Dummies" series. Perkins also has extensive experience working in home health with medically fragile pediatric patients.