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What to Expect When Dying of Liver Cancer
Terminal liver cancer is unpleasant no matter how you look at it, but understanding what to expect can help you prepare yourself mentally for the end 23. Where the cancer has metastasized to other areas of the body and the hope of forcing the cancer into remission has ended, death from liver cancer becomes an inevitability rather than a possibility 3.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Liver Cancer
According to Medline Plus, liver cancer is normally seen in individuals who are older--the initial diagnosis is rarely made in someone younger than 50 years of age 3. The risk of developing liver cancer is exacerbated by abuse of alcohol, an excess of iron in the body, or the presence of certain viruses such as hepatitis B and C 3.
Metastatic Cancer
What to Expect in the Last Stage of Cancer
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According to the National Cancer Institute, once liver cancer metastasizes, the goal shifts from aiming for a remission to aiming to extend life as long as possible, but understanding that the fight against liver cancer is no longer winnable 3. Symptoms to expect where your cancer has metastasized and you are dying of liver cancer include unexplained weight loss and pain throughout the body as the cancer moves into the bones and other organs 3.
Anecdotal Reports
Individuals on the website Medhelp.com experiencing or living with someone with end-stage liver cancer have reported that in many cases dying from liver cancer is a rather subdued event 3. Many individuals reported that the patient simply suffered from increasing levels of fatigue until he was on permanent bed rest coupled with a complete loss of appetite. This situation normally persists until the end.
- Individuals on the website Medhelp.com experiencing or living with someone with end-stage liver cancer have reported that in many cases dying from liver cancer is a rather subdued event 3.
Health Care
Final Signs Before Death With Metastatic Breast Cancer
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As liver cancer nears its conclusion, expect that the goals of medical care providers will shift accordingly 3. It is likely that many medical procedures will cease, and the focus will shift to pain relief rather than attempting to maximize the amount of time the patient spends in an impaired state. The possibility of hospice care is one alternative for the late-stage liver cancer patient, which is a facility dedicated to making terminally ill patients as comfortable as possible 3.
Psychology
According to the Mayo Clinic, there is a psychological process related to impending death, culminating in acceptance. Although you might be familiar with the various "stages" of death (such as anger and denial), do not assume that your individual experience will mirror this generic process. In general, the best thing that you can do is to take full advantage of your life before it ends.
Related Articles
References
- Coping with Advanced Cancer
- Terminal Illness
- End Stage Liver Cancer
- El-Serag HB. Epidemiology of viral hepatitis and hepatocellular carcinoma. Gastroenterology. 2012;142(6):1264‐1273.e1. doi:10.1053/j.gastro.2011.12.061
- Recio-Boiles A, Waheed A, Babiker HM. Cancer, Liver. [Updated 2019 Aug 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK448337/
- Trefts E, Gannon M, Wasserman DH. The liver. Curr Biol. 2017;27(21):R1147‐R1151. doi:10.1016/j.cub.2017.09.019
- Musick SR, Smith M, Babiker HM. Cancer, Hepatoblastoma. [Updated 2020 Jan 13]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK534795/
- Dimitroulis D, Damaskos C, Valsami S, et al. From diagnosis to treatment of hepatocellular carcinoma: An epidemic problem for both developed and developing world. World J Gastroenterol. 2017;23(29):5282‐5294. doi:10.3748/wjg.v23.i29.5282
- Suh JK, Lee J, Lee JH, Shin S, Tchoe HJ, Kwon JW. Risk factors for developing liver cancer in people with and without liver disease. PLoS One. 2018;13(10):e0206374. Published 2018 Oct 29. doi:10.1371/journal.pone.0206374
- Ringelhan M, McKeating JA, Protzer U. Viral hepatitis and liver cancer [published correction appears in Philos Trans R Soc Lond B Biol Sci. 2018 Jan 5;373(1737):]. Philos Trans R Soc Lond B Biol Sci. 2017;372(1732):20160274. doi:10.1098/rstb.2016.0274
- Matsushita H, Takaki A. Alcohol and hepatocellular carcinoma. BMJ Open Gastroenterol. 2019;6(1):e000260. Published 2019 Apr 3. doi:10.1136/bmjgast-2018-000260
- Reyes CV. Hepatocellular Carcinoma in Wilson Disease-related Liver Cirrhosis. Gastroenterol Hepatol (N Y). 2008;4(6):435‐437.
- Fung BM, Lindor KD, Tabibian JH. Cancer risk in primary sclerosing cholangitis: Epidemiology, prevention, and surveillance strategies. World J Gastroenterol. 2019;25(6):659‐671. doi:10.3748/wjg.v25.i6.659
- Liu Y, Wu F. Global burden of aflatoxin-induced hepatocellular carcinoma: a risk assessment. Environ Health Perspect. 2010;118(6):818‐824. doi:10.1289/ehp.0901388
- Volk ML, Marrero JA. Early detection of liver cancer: diagnosis and management. Curr Gastroenterol Rep. 2008;10(1):60‐66. doi:10.1007/s11894-008-0010-2
- Poynard T, Peta V, Deckmyn O, et al. LCR1 and LCR2, two multi-analyte blood tests to assess liver cancer risk in patients without or with cirrhosis. Aliment Pharmacol Ther. 2019;49(3):308‐320. doi:10.1111/apt.15082
- Oliva MR, Saini S. Liver cancer imaging: role of CT, MRI, US and PET. Cancer Imaging. 2004;4 Spec No A(Spec No A):S42‐S46. Published 2004 Apr 2. doi:10.1102/1470-7330.2004.0011
- Di Tommaso L, Spadaccini M, Donadon M, et al. Role of liver biopsy in hepatocellular carcinoma. World J Gastroenterol. 2019;25(40):6041‐6052. doi:10.3748/wjg.v25.i40.6041
- PDQ Adult Treatment Editorial Board. Adult Primary Liver Cancer Treatment (PDQ®): Health Professional Version. 2019 Oct 3. In: PDQ Cancer Information Summaries [Internet]. Bethesda (MD): National Cancer Institute (US); 2002-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK66030/
- Young M, John S. Hepatic Chemoembolization. [Updated 2019 Dec 15]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507822/
- Gish RG, Finn RS, Marrero JA. Extending survival with the use of targeted therapy in the treatment of hepatocellular carcinoma. Gastroenterol Hepatol (N Y). 2013;9(4 Suppl 2):1‐24.
- Shi M, Guo RP, Lin XJ, et al. Partial hepatectomy with wide versus narrow resection margin for solitary hepatocellular carcinoma: a prospective randomized trial. Ann Surg. 2007;245(1):36‐43. doi:10.1097/01.sla.0000231758.07868.71
- Jadlowiec CC, Taner T. Liver transplantation: Current status and challenges. World J Gastroenterol. 2016;22(18):4438‐4445. doi:10.3748/wjg.v22.i18.4438
- Chen CP. Role of Radiotherapy in the Treatment of Hepatocellular Carcinoma. J Clin Transl Hepatol. 2019;7(2):183‐190. doi:10.14218/JCTH.2018.00060
- Izzo F, Granata V, Grassi R, et al. Radiofrequency Ablation and Microwave Ablation in Liver Tumors: An Update. Oncologist. 2019;24(10):e990‐e1005. doi:10.1634/theoncologist.2018-0337
- Noonan A, Pawlik TM. Hepatocellular carcinoma: an update on investigational drugs in phase I and II clinical trials. Expert Opin Investig Drugs. 2019;28(11):941‐949. doi:10.1080/13543784.2019.1677606
- Woodrell CD, Hansen L, Schiano TD, Goldstein NE. Palliative Care for People With Hepatocellular Carcinoma, and Specific Benefits for Older Adults. Clin Ther. 2018;40(4):512-525.
- Momin B, Millman AJ, Nielsen DB, Revels M, Steele CB. Promising practices for the prevention of liver cancer: a review of the literature and cancer plan activities in the National Comprehensive Cancer Control Program. Cancer Causes Control. 2018;29(12):1265‐1275. doi:10.1007/s10552-018-1094-0
- Momin BR, Pinheiro PS, Carreira H, Li C, Weir HK. Liver cancer survival in the United States by race and stage (2001-2009): Findings from the CONCORD-2 study. Cancer. 2017;123 Suppl 24(Suppl 24):5059‐5078. doi:10.1002/cncr.30820
- Domínguez-Cabello E, Martín-Rodríguez A, Pérez-San-Gregorio MA, Fernández-Jiménez E, Sousa-Martín JM, Bernardos-Rodríguez A. Coping strategies in liver patients as a function of relatives' anxiety level. Transplant Proc. 2012;44(9):2616‐2618. doi:10.1016/j.transproceed.2012.09.106
- Nguyen DL, Chao D, Ma G, Morgan T. Quality of life and factors predictive of burden among primary caregivers of chronic liver disease patients. Ann Gastroenterol. 2015;28(1):124‐129.
- Forner, A., Reig, M., and J. Bruix. Hepatocellular Carcinoma. Lancet. 2018 Jan 4. (Epub ahead of print).
- National Cancer Institute. Primary Liver Cancer Treatment (PDQ)—Health Professional Version. Updated -2/06/18. https://www.cancer.gov/types/liver/hp/adult-liver-treatment-pdq
- Woodrell, C., Hansen, L., Schiano, T., and N. Goldstein. Palliative Care for People With Hepatocellular Carcinoma, and Specific Benefits for Older Adults. Clinical Therapeutics. 2018 Mar 20. (Epub ahead of print).
Writer Bio
TS Jordan is an Ohio licensed attorney living and practicing out of the Cleveland area. In addition to his Juris Doctorate, he holds a Bachelors' Degree in Information Systems. He has been writing professionally for less than a year.