What does fact checked mean?
At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- Centers for Disease Control and Prevention: Parvovirus B19 (Fifth Disease)
- Centers for Disease Control and Prevention: Hand, Foot, and Mouth Disease
- MayoClinic.com: Hand-foot-and-mouth disease prevention
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
How to Diagnose Fifth Disease Vs. Hand, Foot and Mouth Disease
Fifth disease, or erythema infectiosum, and hand, foot and mouth disease (HFMD) are both common childhood viral infections spread by direct contact 12. Fifth disease, caused by human Parvovirus B19, is usually dismissed as a cold until a red rash that looks as though the child has been slapped appears on the cheeks. HFMD is primarily associated with coxsackievirus A16 and is characterized by similar mild symptoms plus small blisters in the mouth and on the extremities. According to MayoClinic.com, both viruses are best prevented by regular hand washing and using a diluted bleach solution to sanitize common areas in homes, schools and daycares 2.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Fifth Disease
Find out how fifth disease is spread and who might contract the virus. Direct contact, such as sharing cups or exposure to nasal droplets, passes this mild illness from person to person, but cold-like symptoms might not appear for up to three weeks. Fifth disease targets children, but adults can get it, too.
Herpangina in Adults
Learn More
Educate yourself about the outward signs of fifth disease. In addition to the slapped-cheek rash, you also will see a pink, lacy rash resembling a tablecloth pattern on the torso and limbs; both might last up to 10 days. When the rashes appear, the child is no longer contagious and can return to school or daycare.
Manage fifth disease by trying to prevent it and then allowing it to run its course if your child contracts it. The rash might be itchy, and your child might run a low fever, have a sore throat and feel general malaise. Alleviate symptoms with acetaminophen, ibuprofen and antihistamines.
- Find out how fifth disease is spread and who might contract the virus.
- Direct contact, such as sharing cups or exposure to nasal droplets, passes this mild illness from person to person, but cold-like symptoms might not appear for up to three weeks.
Hand, Foot and Mouth Disease
Rashes Following a Fever in Children
Learn More
Find out how HFMD is spread and who can contract the virus. HFMD mostly affects children who are 10 and younger, but adults and older children are susceptible to it as well. Your child is most contagious during the first week of the illness but can spread the virus — after symptoms resolve — for several weeks by direct contact with respiratory secretions or infected stool.
Educate yourself about the signs and symptoms of HFMD. This disease presents in a similar manner to fifth disease with vague symptoms of a cold, but the incubation time is shorter with symptoms beginning within five days of exposure. Your child likely will have a sore throat and fever. Uncomfortable sores in the mouth that appear a few days after the fever starts will help you or your physician diagnose HFMD. A non-itchy rash and blisters will develop on the toes, feet, fingers, hands and sometimes the buttocks.
Manage HFMD by trying to prevent it with good hygiene and then allowing it to run its course, usually within seven days. Focus on soothing foods and beverages such as ice pops and milkshakes to stay hydrated and minimize discomfort from mouth blisters. Use over-the-counter pain relievers as needed.
Tips
Each of these contagious diseases can be spread by people who show no symptoms, so teaching and using good hygiene is the best defense.
You can have hand, foot and mouth disease more than once because it is caused by more than one virus. HFMD is most common in the summer and fall, but it affects people living in warm climates year-round. Hand, foot and mouth disease is not the same as animal foot-and-mouth disease.
Fifth disease (Parvovirus B19) is not caused by the animal Parvovirus.
Warnings
Fifth disease can be more risky for pregnant women, those who have sickle cell disease and similar types of chronic anemia or compromised immune systems. About 50 percent of adults are immune to fifth disease, but in rare cases exposure can cause miscarriage during early pregnancy.
If your child is chronically anemic, the characteristic fifth disease rash might not appear, so call your doctor if your child is constantly feverish, pale, weak or tired.
Rare complications do exist for HFMD, including viral meningitis and encephalitis. Meningitis can require hospitalization; encephalitis, which is a type of brain inflammation, can be fatal.
- Find out how HFMD is spread and who can contract the virus.
- This disease presents in a similar manner to fifth disease with vague symptoms of a cold, but the incubation time is shorter with symptoms beginning within five days of exposure.
Related Articles
References
- Centers for Disease Control and Prevention: Hand, Foot, and Mouth Disease
- MayoClinic.com: Hand-foot-and-mouth disease prevention
- Crawford F. Athlete's foot. BMJ Clin Evid. 2009;2009:1712.
- American Academy of Dermatology Association. How to prevent athlete's foot.
- Cleveland Clinic. Poison Plants: Poison Ivy, Poison Oak & Poison Sumac. Updated December 20, 2018.
- Centers for Disease Control and Prevention. Symptoms and Diagnosis of Hand, Foot, and Mouth Disease. Updated December 6, 2019.
- Centers for Disease Control and Prevention. Treat Hand, Foot, and Mouth Disease. Updated December 6, 2019.
- Sullivan T, de Barra E. Diagnosis and management of cellulitis. Clin Med (Lond). 2018;18(2):160–163. doi:10.7861/clinmedicine.18-2-160
- National Eczema Association. Dyshidrotic Eczema.
- Matthys E, Zahir A, Ehrlich A. Shoe allergic contact dermatitis. Dermatitis. 2014;25(4):163-71. doi:10.1097/DER.0000000000000049
- Centers for Disease Control and Prevention. Scabies. Updated October 31, 2017.
Tips
- Each of these contagious diseases can be spread by people who show no symptoms, so teaching and using good hygiene is the best defense.
- You can have hand, foot and mouth disease more than once because it is caused by more than one virus. HFMD is most common in the summer and fall, but it affects people living in warm climates year-round. Hand, foot and mouth disease is not the same as animal foot-and-mouth disease.
- Fifth disease (Parvovirus B19) is not caused by the animal Parvovirus.
Warnings
- Fifth disease can be more risky for pregnant women, those who have sickle cell disease and similar types of chronic anemia or compromised immune systems. About 50 percent of adults are immune to fifth disease, but in rare cases exposure can cause miscarriage during early pregnancy.
- If your child is chronically anemic, the characteristic fifth disease rash might not appear, so call your doctor if your child is constantly feverish, pale, weak or tired.
- Rare complications do exist for HFMD, including viral meningitis and encephalitis. Meningitis can require hospitalization; encephalitis, which is a type of brain inflammation, can be fatal.
Writer Bio
Emily Claassen has been a writer, editor and publication designer since 1986. During college, she was a reporter for a daily newspaper. Since then, she has worked primarily for educational institutions, research organizations and nonprofit clients, writing and editing a variety of material. She has a Bachelor of Journalism from the University of Missouri-Columbia.