Calcium Channel Blockers and Swelling Feet
Doctors prescribe calcium channel blockers to treat a number of conditions, including high blood pressure, migraine headaches, circulatory conditions and complications of brain aneurysms, according to MayoClinic.com 12. The common side effects of calcium channel blockers include peripheral edema, or swelling of the feet, ankles and legs from the buildup of fluid 1.
Calcium Channel Blockers
Calcium channel blockers lower blood pressure by blocking the entry of calcium into the cells of the heart and the walls of blood vessels and relaxing vessels and tissues to allow blood to flow more freely, explains MayoClinic.com 12. Calcium channel blockers, also called calcium antagonists, come in several forms, including short-acting medications and the slow-release, long-acting medications 1. Verapamil, nifedipine and diltiazem are among the eight calcium channel blockers listed by MedlinePlus, a website from the U.S. National Library of Medicine and the National Institutes of Health 14. Physicians often prescribe calcium channel blockers with medications to lower cholesterol, called statins, and with other types of medication for high blood pressure 1.
Edema
Causes of Swollen Lower Legs and Feet
Learn More
Swelling feet result from edema. The process that causes edema is a complex biological reaction involving leaking blood vessels, or capillaries, and the kidneys, which respond by retaining more water and sodium to make up for the fluid lost from blood vessels. These reactions cause fluid to build up in your body, which again causes more leakage from your capillaries. Fluid builds up in your body’s tissues, and the tissues swell. Untreated edema can cause added swelling that becomes painful, stiffness, stretched skin and poor blood circulation. Failure to treat your edema can lead to trouble walking, scarring of the tissues in your body and damage to your skin, arteries and joints, notes MayoClinic.com 2.
- Swelling feet result from edema.
- These reactions cause fluid to build up in your body, which again causes more leakage from your capillaries.
Swelling Feet
Swelling of the feet caused by calcium channel blockers is a painless condition 1. Swelling in the feet is more noticeable because of the effect of gravity on fluid in your body. Fluid retention might not be limited to your feet. The buildup of fluid in the feet and legs can indicate a serious condition, such as kidney, liver or heart failure, so it is important to confirm with your doctor that your swelling results from the calcium channel blocker.
- Swelling of the feet caused by calcium channel blockers is a painless condition 1.
- The buildup of fluid in the feet and legs can indicate a serious condition, such as kidney, liver or heart failure, so it is important to confirm with your doctor that your swelling results from the calcium channel blocker.
Prevention
How to Relieve Ankle Swelling Naturally
Learn More
St. John’s Mercy Health Care recommends that you call your doctor and ask how to relieve the swelling in your feet. Although your swelling is probably painless, you might experience discomfort from the buildup of fluid. You can prevent added swelling by refraining from sitting or standing in one position without moving for long periods. When you drive or take a flight, take time to get up and walk around. Don’t wear clothing that restricts circulation in your legs. Engage in regular exercise, and maintain a healthy weight, advises MayoClinic.com 2.
- St. John’s Mercy Health Care recommends that you call your doctor and ask how to relieve the swelling in your feet.
Treatment
To reduce swelling, lie down, and elevate your feet above your heart, suggests MedlinePlus 3. Perform leg exercises to move fluid back to your heart, and wear support hose if necessary. A low-sodium diet can reduce swelling. MayoClinic.com recommends a massage with a firm, stroking pressure toward the heart to reduce swelling 2. Your doctor might prescribe a diuretic, known as a water or fluid pill, to reduce the swelling in your feet.
Warning
FamilyDoctor.org, a website from the American Academy of Family Physicians, warns that you should contact your doctor immediately if you have shortness of breath in addition to your swollen feet 5.
Related Articles
References
- MayoClinic.com: Calcium Channel Blockers
- MayoClinic.com: Edema
- MedlinePlus: Foot, Leg and Ankle Swelling
- St. John’s Mercy Health Care: Calcium Channel Blockers for Heart Failure
- FamilyDoctor.org: Edema
- Calcium channel blockers in the management of stable angina pectoris. April 2019.
- Ghosh D, Syed AU, Prada MP, et al. Calcium channels in vascular smooth muscle. Adv Pharmacol. 2017;78:49-87. doi:10.1016/bs.apha.2016.08.002
- American Heart Association. Conduction disorders. Updated September 30, 2016.
- Godfraind T. Discovery and development of calcium channel blockers. Front Pharmacol. 2017;8:286. doi: 10.3389/fphar.2017.00286
- Humbert X, Roule V, Milliez P, Alexandre J. Verapamil and vasospastic angina: underuse in the elderly population. J Geriatr Cardiol. 2017;14(7):430-435. doi:10.11909/j.issn.1671-5411.2017.07.004
- Sica DA. Current concepts of pharmacotherapy in hypertension: combination calcium channel blocker therapy in the treatment of hypertension. J Clin Hypertens (Greenwich). 2001;3(5):322-7. doi:10.1111/j.1524-6175.2001.00484.x
- Sica DA. Current concepts of pharmacotherapy in hypertension: combination calcium channel blocker therapy in the treatment of hypertension. J Clin Hypertens (Greenwich). 2001;3(5):322-7. doi:10.1111/j.1524-6175.2001.00484.x
- Gersh BJ, Maron BJ, Bonow RO, et al. 2011 ACCF/AHA guideline for the diagnosis and treatment of hypertrophic cardiomyopathy: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation. 2011;124(24):2761-96. doi:10.1161/CIR.0b013e318223e230
- Haller H. Effective management of hypertension with dihydropyridine calcium channel blocker-based combination therapy in patients at high cardiovascular risk. Int J Clin Pract. 2008;62(5):781-90. doi:10.1111/j.1742-1241.2008.01713.x
- Oregon Evidence-based Practice Center Oregon Health & Science University. Drug class review on calcium channel blockers. Updated June 2004.
- Cleveland Clinic. Hypertrophic cardiomyopathy guide. Updated May 2009.
- NIH MedlinePlus. Verapamil. Updated October 15, 2017.
- NIH MedlinePlus. Diltiazem. Updated October 15, 2017.
- Ioulios P, Charalampos M, Efrossini T. The spectrum of cutaneous reactions associated with calcium antagonists: a review of the literature and the possible etiopathogenic mechanisms. Dermatol Online J. 2003;9(5):6.
- McKeever RG, Hamilton RJ. Calcium Channel Blockers. In: StatPearls [Internet]. Updated March 29, 2020.
- Fihn SD, Gardin JM, Abrams J, et al. 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management ofPpatients with Stable Ischemic Heart Disease: a Report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Circulation 2012; 126:e354.
- Gersh BJ, Maron BJ, Bonow RO, et al. 2011 ACCF/AHA Guideline for the Diagnosis and Treatment of Hypertrophic Cardiomyopathy: Executive Summary: a Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2011; 124:2761.
- James PA, Oparil S, Carter BL, et al. 2014 Evidence-Based Guideline For The Management Of High Blood Pressure In Adults: Report From The Panel Members Appointed to the Eighth Joint National Committee (JNC 8). JAMA 2014; 311:507.doi: 10.1001/jama.2013.28442
Writer Bio
Gail Sessoms, a grant writer and nonprofit consultant, writes about nonprofit, small business and personal finance issues. She volunteers as a court-appointed child advocate, has a background in social services and writes about issues important to families. Sessoms holds a Bachelor of Arts degree in liberal studies.