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Synthroid Reactions to Garlic or Other Vitamins

By Lynda Lampert

Taking prescription drugs with herbs and vitamins is a tricky prospect. You are never sure what herb will interact with something your doctor has prescribed. What's worse, those interactions might harm you. Synthroid does not interact with garlic, but it does interact with other vitamins. Before taking prescription drugs with anything over the counter, ask your doctor for advice. Even better, ask your pharmacist, too. They are experts on all drugs, and can tell you exactly which medications are safe to mix.


Levothyroxine, or synthroid, is a replacement hormone for people who have little or no thyroid hormones created by their own body. You may need this drug if you had your thyroid surgically removed or if you have hypothyroidism, which means your thyroid does not produce enough hormone on its own. This drug is also helpful in preventing or treating goiters, which are enlargements of the thyroid because of hormone imbalances, radiation, surgery or cancer.


Synthroid reacts with some vitamins, but it does not have any interactions with garlic. Use caution if you use this hormone replacement and alpha-lipoic acid, magnesium, iron or lemon balm, according to the University of Maryland Medical Center. Other drug and vitamin interactions include calcium supplements such as calcium carbonate, sucralfate, sodium polystyrene sulfonate, antacids that contain aluminum and the cholesterol-lowering drugs such as cholestyramine. The drugs lithium, amiodarone and certain antidepressants also can affect how synthroid is absorbed, so mention them to your doctor if you are taking them.

Side Effects

Since synthroid mimics a naturally occurring hormone, few side effects are associated with it. However, if side effects are noted, report them to your doctor. You may need your dosage adjusted. These side effects include headache, trouble sleeping, irritability, hot flashes, sweating, irregular menstrual period, appetite changes and possible changes in your weight. Occasionally, hair loss is noted. If you notice signs of an allergic reaction such as hives, itching, swelling of the tongue or trouble breathing, contact your doctor immediately.


Synthroid has some specific instructions in order for it to work most effectively. Take synthroid with a full glass of water to prevent it from dissolving and swelling in your throat. It might cause you to choke or gag. You need to take it on an empty stomach and 30 minutes before you eat any food for the medication to fully absorb. Do not abruptly stop taking this medication. You might need to have blood tests occasionally to determine whether your medication is regulating your thyroid levels correctly. You doctor may need to adjust your medication dosage based on the blood tests.

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