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At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- Journal of Agricultural and Food Chemistry: Helichrysum and Grapefruit Extracts Inhibit Carbohydrate Digestion and Absorption, Improving Postprandial Glucose Levels and Hyperinsulinemia in Rats
- Journal of Agricultural and Food Chemistry: Helichrysum and Grapefruit Extracts Inhibit Carbohydrate Digestion and Absorption, Improving Postprandial Glucose Levels and Hyperinsulinemia in Rats
- Cardiovascular Journal of Africa: The Grapefruit: An Old Wine in a New Glass? Metabolic and Cardiovascular Perspectives
- Cardiovascular Journal of Africa: The Grapefruit: An Old Wine in a New Glass? Metabolic and Cardiovascular Perspectives
- Journal of Medicinal Food: The Effects of Grapefruit on Weight and Insulin Resistance: Relationship to the Metabolic Syndrome
- Journal of Medicinal Food: The Effects of Grapefruit on Weight and Insulin Resistance: Relationship to the Metabolic Syndrome
- Linus Pauling Institute: Flavonoids
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
Does Grapefruit Aid in Digestion?
Although the fiber in grapefruit undoubtedly aids your digestion by moving things along and by helping to keep you regular, promising evidence reveals that other nutrients in grapefruit could also optimize your digestion. This is particularly true if you have type-2 diabetes or are at risk for getting type-2 diabetes, as grapefruit improves the digestive hormone insulin. Make sure your doctor says it is OK before you add grapefruit in any form to your diet, though, since grapefruit can interact with many different medications.
May Improve Insulin Levels in Your Blood
Researchers who published an article on nutrition errors and myths in 2013 in the journal "Nutricion Hospitalara" concluded that evidence tends to support grapefruit as a weight-loss food 1. This could likely be accredited to how grapefruit extract may block the digestion and absorption of some of the carbohydrates you eat. One study published in 2013 in the "Journal of Agricultural and Food Chemistry" showed that frapefruit extract given to laboratory rats did just that. This led to lower blood sugars after eating, and improved insulin levels in the blood. Insulin is a digestive hormone that plays a key role in blood sugar metabolism, so proper insulin levels in your body are important for your digestive health.
- Researchers who published an article on nutrition errors and myths in 2013 in the journal "Nutricion Hospitalara" concluded that evidence tends to support grapefruit as a weight-loss food 1.
- This could likely be accredited to how grapefruit extract may block the digestion and absorption of some of the carbohydrates you eat.
May Help Metabolism
Can You Eat Grapefruit While Taking Crestor?
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Metabolic syndrome consists of a number of conditions, including abdominal obesity, high cholesterol, elevated blood pressure and elevated blood sugar. Combined, these conditions lead to a risk for type-2 diabetes. Researchers of a study on grapefruit and metabolic syndrome published in "Journal of Medicinal Food" in 2006 found that consumption of grapefruit, whether eaten as half the whole fruit or in juice or capsule form, led to more weight loss and lower blood sugar in 91 obese people 45.
How Grapefruit Works on Your Metabolism
A flavonoid is an antioxidant compound found in many foods. A majority of the flavonoid content in grapefruits are hesperidin and naringin, according to researchers of a review article published in 2010 in "Cardiovascular Journal of Africa." The researchers explain that naringin has been shown to act somewhat like insulin and may be involved in fat metabolism. Researchers of this review also explain that vitamin C, another nutrient found in high quantities in grapefruit, naringin and hesperidin, may improve type-2 diabetes and metabolic system measurements by regulating and affecting several digestive enzymes.
- A flavonoid is an antioxidant compound found in many foods.
- Researchers of this review also explain that vitamin C, another nutrient found in high quantities in grapefruit, naringin and hesperidin, may improve type-2 diabetes and metabolic system measurements by regulating and affecting several digestive enzymes.
Grapefruit Gets Things Moving
Side Effects of Grapefruit Seed Extract
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Grapefruit is a good source of fiber, and it contains both soluble and insoluble fiber -- both of which can help improve digestion. Soluble fiber helps lower cholesterol and control blood sugars, which are metabolic syndrome parameters, while insoluble fiber prevents constipation, thus improving digestion. One medium grapefruit has about 3.2 grams of fiber. Of these 3.2 grams of fiber, 2.2 grams is soluble fiber and 1 gram is insoluble fiber.
- Grapefruit is a good source of fiber, and it contains both soluble and insoluble fiber -- both of which can help improve digestion.
Related Articles
References
- Nutricion Hospitalaria: Errors and Myths in Feeding and Nutrition: Impact on the Problems of Obesity
- Journal of Agricultural and Food Chemistry: Helichrysum and Grapefruit Extracts Inhibit Carbohydrate Digestion and Absorption, Improving Postprandial Glucose Levels and Hyperinsulinemia in Rats
- Encyclopedia Britannica: Human Digestive System: Individual Hormones
- Cardiovascular Journal of Africa: The Grapefruit: An Old Wine in a New Glass? Metabolic and Cardiovascular Perspectives
- Journal of Medicinal Food: The Effects of Grapefruit on Weight and Insulin Resistance: Relationship to the Metabolic Syndrome
- Linus Pauling Institute: Flavonoids
- Clemson University: Nutrient Claims on Food Labels
- Grapefruit, raw, pink and red, all areas. USDA FoodData Central. Updated April 2019.
- Vitamin C - Fact Sheet for Health Professionals. National Institutes of Health (NIH). Office Of Dietary Supplements. Updated July 2019
- Chow O, Barbul A. Immunonutrition: Role in wound healing and tissue regeneration. Adv Wound Care (New Rochelle). 2014;3(1):46–53. doi:10.1089/wound.2012.0415
- Vitamin A Fact Sheet for Professionals. National Institutes of Health Office of Dietary Supplements. February 14, 2020
- Rasmussen HM, Johnson EJ. Nutrients for the aging eye. Clin Interv Aging. 2013;8:741–748. doi:10.2147/CIA.S45399
- Chen P, Zhang W, Wang X, Zhao K, Negi D, Zhou L, et al. Lycopene and risk of prostate cancer: A systematic review and meta-analysis. Medicine (Baltimore). 2015;94(33):e1260. doi:10.1097/MD.0000000000001260
- Vissers MCM, Das AB. Potential mechanisms of action for vitamin C in cancer: Reviewing the evidence. Front Physiol. 2018;9:809. doi:10.3389/fphys.2018.00809
- Dow CA, Going SB, Chow H-HS, Patil BS, Thomson CA. The effects of daily consumption of grapefruit on body weight, lipids, and blood pressure in healthy, overweight adults. Metabolism. 2012;61(7):1026-1035. doi:10.1016/j.metabol.2011.12.004
- Zhao CN, Meng X, Li Y, et al. Fruits for prevention and treatment of cardiovascular diseases. Nutrients. 2017;9(6):598. doi:10.3390/nu9060598
- Panche AN, Diwan AD, Chandra SR. Flavonoids: An overview. J Nutr Sci. 2016;5:e47. doi:10.1017/jns.2016.41
- Bourrier T, Pereira C. Allergy to citrus juice. Clin Transl Allergy. 2013;3(Suppl 3):P153. Published 2013 Jul 25. doi:10.1186/2045-7022-3-S3-P153
- Grapefruit Juice and Some Drugs Don't Mix. U.S. Food and Drug Administration. FDA Consumer Updates. Updated July 2017.
- Grapefruit juice and statins. Harvard Medical School - Healthbeat. Harvard Health Publishing. Updated September 2019.
- Bailey DG, Dresser G, Arnold JM. Grapefruit-medication interactions: Forbidden fruit or avoidable consequences?. CMAJ. 2013;185(4):309-16. doi:10.1503/cmaj.120951
- Kanellis A, Manganaris G. Fruit Ripening. (Nath P, Bouzayen M, Mattoo A, Pech J, eds.). Oxfordshire: CABI; 2014:110.
- Wanlapa S, Wachirasiri K, Sithisam-ang D, Suwannatup T. Potential of selected tropical fruit peels as dietary fiber in functional foods. International Journal of Food Properties. 2015;18(6):1306-1316. doi:10.1080/10942912.2010.535187
- Murphy MM, Barraj LM, Rampersaud GC. Consumption of grapefruit is associated with higher nutrient intakes and diet quality among adults, and more favorable anthropometrics in women, NHANES 2003-2008. Food Nutr Res. 2014;58:10.3402/fnr.v58.22179. doi:10.3402/fnr.v58.22179
Writer Bio
Jamie Yacoub is a clinical outpatient Registered Dietitian, expert in nutrition and author of her cookbook "Modern Guide to Food and Eating: Low Glycemic Recipes". She obtained a Bachelor of Science in clinical nutrition from UC Davis and an MPH in nutrition from Loma Linda University. Yacoub then completed her dietetic internship as an intern for a Certified Specialist in sports nutrition and at a top-100 hospital.