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- MedlinePlus: Licorice
- National Center for Complementary and Alternative Medicine; Licorice Root; June 2006
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
Does Black Licorice Help Induce Labor
Licorice root and licorice root extract flavor foods and might help to treat health conditions including heartburn, canker sores, peptic ulcers and upper respiratory infections. Some women also consume licorice in the hopes of inducing labor, but there isn't sufficient evidence for the effectiveness of licorice for any of these purposes, according to the National Center for Complementary and Alternative Medicine 3.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Licorice Effect During Pregnancy
Licorice root and licorice extract contain an ingredient called glycyrrhizin, which might have either an estrogen-like or an anti-estrogen effect. It might cause uterine contractions, so consuming large amounts of licorice root or licorice that contains licorice extract might bring on labor in some women, but it also could have dangerous side effects and not bring on labor, so it isn't a good idea to intentionally consume large amounts of this substance during pregnancy.
Glycyrrhizin Content
Side Effects of Deglycyrrhizinated Licorice
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Not all black licorice candy contains licorice extract. Many licorice candies are flavored with anise rather than licorice extract. These candies would not induce labor. Small amounts of black licorice candy made with licorice extract also are unlikely to induce labor, according to eMedTV, but large amounts might and so are not advised during pregnancy.
- Not all black licorice candy contains licorice extract.
- Many licorice candies are flavored with anise rather than licorice extract.
Side Effects and Safety
Large amounts of licorice can cause side effects that are particularly dangerous during pregnancy, including low levels of potassium in your blood, high blood pressure, paralysis and brain damage. These side effects are more likely to occur if you have heart disease, kidney disease or high blood pressure, or take more than 30 g of licorice each day for a few weeks. It also might interact with medications, including diuretics, corticosteroids, blood thinners, blood pressure medications, furosemide, digoxin, estrogens, ACE inhibitors, MAO inhibitors, laxatives, diabetes medication and ethacrynic acid.
Considerations
Does Fennel Contain Black Licorice?
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Don't consume black licorice in large amounts during pregnancy without speaking with your doctor. Black licorice isn't guaranteed to induce labor and could cause dangerous side effects if it contains glycyrrhizin. Follow the advice of your doctor regarding safe methods to induce labor rather than attempting to do this on your own.
Related Articles
References
- University of Maryland Medical Center: Licorice
- eMedTV; Licorice and Pregnancy; Kristi Monson, PharmD and Arthur Schoenstadt, MD
- National Center for Complementary and Alternative Medicine; Licorice Root; June 2006
- NIH National Center for Complementary and Integrative Health. Licorice root. Updated December 1, 2016.
- Raveendra KR, Jayachandra, Srinivasa V, et al. An extract of glycyrrhiza glabra (GutGard)alleviates symptoms of functional dyspepsia: a randomized, double-blind, placebo-controlled study. Evidence-Based Complementary and Alternative Medicine. 2012;2012:1-9. doi:10.1155/2012/216970
- Messier C, Epifano F, Genovese S, Grenier D. Licorice and its potential beneficial effects in common oro-dental diseases. Oral Dis. 2012;18(1):32-39. doi:10.1111/j.1601-0825.2011.01842.x
- Shi Q, Hou Y, Yang Y, Bai G. Protective effects of glycyrrhizin against β2-adrenergic receptor agonist-induced receptor internalization and cell apoptosis. Biol. Pharm. Bull. 2011;34(5):609-617. doi:10.1248/bpb.34.609
- Tsao S, Yin M. Antioxidative and antiinflammatory activities of asiatic acid, glycyrrhizic Acid, and oleanolic acid in human bronchial epithelial cells. J. Agric. Food Chem. 2015;63(12):3196-3204.
- Zhao H, Zhang X, Chen X, et al. Isoliquiritigenin, a flavonoid from licorice, blocks M2 macrophage polarization in colitis-associated tumorigenesis through downregulating PGE2 and IL-6. Toxicology and Applied Pharmacology. 2014;279(3):311-321. doi:10.1016/j.taap.2014.07.001
- Nahidi F, Zare E, Mojab F, Alavi-Majd H. Effects of licorice on relief and recurrence of menopausal hot flashes. Iranian Journal of Pharmaceutical Research: IJPR. 2012;11(2):541-8.
- Hajiaghamohammadi AA, Zargar A, Oveisi S, Samimi R, Reisian S. To evaluate of the effect of adding licorice to the standard treatment regimen of helicobacter pylori. The Brazilian Journal of Infectious Diseases. 2016;20(6):534-538. doi: 10.1016/j.bjid.2016.07.015
- Irani M, Sarmadi M, Bernard F, Ebrahimi Pour GH, Shaker Bazarnov H. Leaves antimicrobial activity of Glycyrrhiza glabra L. Iranian Journal of Pharmaceutical Research: IJPR. 2010;9(4):425-8.
- Penn State Hershey Milton S. Hershey Medical Center. Licorice.
- Omar HR, Komarova I, El-Ghonemi M, et al. Licorice abuse: time to send a warning message. Therapeutic Advances in Endocrinology. 2012;3(4):125-138. doi:10.1177/2042018812454322
- Räikkönen K, Martikainen S, Pesonen A, et al. Maternal licorice consumption during pregnancy and pubertal, cognitive, and psychiatric outcomes in children. Am J Epidemiol. 2017;185(5):317-328. doi:10.1093/aje/kww172
- Consumer Reports. Food and drug interactions you need to know about. Updated November 4, 2018.
- Winchester Hospital. Library. Updated April 11, 2011.
- Consumer Reports. How to choose supplements wisely. Updated October 30, 2019.
- FDA. Black licorice: Trick or treat? Updated November 6, 2017.
Writer Bio
Based in Massachusetts, Jessica Bruso has been writing since 2008. She holds a master of science degree in food policy and applied nutrition and a bachelor of arts degree in international relations, both from Tufts University.