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Many people who struggle with weight loss may be insulin resistant. One in four Americans may have, or may develop, insulin resistance as a result of a genetic predisposition, according to Sheri Barke, a registered dietitian with College of the Canyons in California. Insulin resistant cells do not efficiently utilize insulin, leaving glucose in the blood, resulting in weight gain and diabetes type 2. Cinnamon and chromium may help to increase insulin sensitivity and assist in weight loss.
Insulin Resistance and Weight Gain
When you eat, insulin is secreted from your pancreas into your blood to facilitate the uptake of blood glucose into your cells. Cells that become resistant to this process cannot utilize the glucose and leave excess amounts of it in your blood. Insulin then takes the excess blood glucose and stores it as fat. At the same time, the excess serum glucose triggers your pancreas to secrete more insulin, which in turn increases your hunger. This vicious circle may lead to weight gain.
- When you eat, insulin is secreted from your pancreas into your blood to facilitate the uptake of blood glucose into your cells.
Cinnamon Allergy Symptoms
In a state of insulin resistance, your cells do not react properly to insulin, leaving high levels of glucose in your bloodstream. Whenever there is glucose circulating in your blood, your pancreas is alerted to send out more insulin. Even though there is plenty of insulin available to complete the task, more insulin is secreted. This is called hyperinsulinemia, which has debilitating consequences on your pancreas. Over time, your pancreas wears out and puts you at risk of diabetes, high cholesterol, obesity and other health problems.
- In a state of insulin resistance, your cells do not react properly to insulin, leaving high levels of glucose in your bloodstream.
- Whenever there is glucose circulating in your blood, your pancreas is alerted to send out more insulin.
Chromium and Weight Loss
Chromium comes in two forms, hexavalent, for industrial use, and trivalent, which your body needs for assisting insulin in getting glucose into your cells. Insulin binds to the glucose molecule, readying it to enter the cell membrane. Chromium unlocks the cell membrane’s door to allow the insulin and glucose to pass. A 2003 research article in "Nutrition Research Reviews" noted that by improving serum chromium levels, blood glucose levels improved, as did insulin sensitivity and lean body mass 2. Because lower insulin levels are required and lean body mass improves, weight loss may result.
- Chromium comes in two forms, hexavalent, for industrial use, and trivalent, which your body needs for assisting insulin in getting glucose into your cells.
- Chromium unlocks the cell membrane’s door to allow the insulin and glucose to pass.
Cinnamon and Weight Loss
Chromium Nicotinate Side Effects
Cinnamon carries an active ingredient called MHCP that is a polyphenol. MHCP is able to imitate insulin and trigger your cells to accept glucose. It also works hand-in-hand with insulin. A December 2003 study in "Diabetes Care" took 60 people with diabetes and gave half cinnamon over 40 days, and the other half a placebo 3. The results showed that taking 1, 3, or 6 g of cinnamon per day reduced serum glucose. Reducing blood glucose may reduce the effects of insulin resistance and lead to weight loss.
- Cinnamon carries an active ingredient called MHCP that is a polyphenol.
- The results showed that taking 1, 3, or 6 g of cinnamon per day reduced serum glucose.
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- Linus Pauling Institute: Chromium
- "Nutrition Research Reviews"; Chromium and Insulin Resistance; Richard A. Anderson; 2003
- "Diabetes Care"; Cinnamon Improves Glucose and Lipids of People With Type 2 Diabetes; Alam Khan, et al.; December 2003
- U.S. Centers for Disease Control and Prevention. Insulin resistance and diabetes. Last reviewed August 12, 2019.
- Wilcox G. Insulin and insulin resistance. Clin Biochem Rev. 2005;26(2):19–39.
- Ritchie RH, Zerenturk EJ, Prakoso D, Calkin AC. Lipid metabolism and its implications for type 1 diabetes-associated cardiomyopathy. J Mol Endocrinol. 2017 May;58(4):R225-R240. doi:10.1530/JME-16-0249
- Volpi, E. and Dickinson, J.M. (2015). Protein metabolism in health and diabetes. In International Textbook of Diabetes Mellitus (eds R.A. DeFronzo, E. Ferrannini, P. Zimmet and K.G.M.M. Alberti). doi:10.1002/9781118387658.ch16
- Colorado State University. Pathophysiology of the Endocrine System. Physiologic effects of insulin.
- University of Berkley, California. Endocrine Pancreas.
Carrie Cross has been writing for profit and pleasure for more than 35 years. Her background includes business, real estate, entrepreneurship, management, health and nutrition. A registered nurse, she has published various pieces, including web content, numerous newspaper and magazine articles and columns and six books.