How Much Resveratrol to Take

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As an antioxidant, resveratrol can help protect your cells from damage caused by free radicals in your body. Increasing your intake of resveratrol, which is found naturally in red wine, may improve the overall health of your heart and can guard this vital organ against disease. Despite this key medicinal benefit, more clinical research is needed to understand how resveratrol works in the human body and what dosage of this antioxidant is necessary to elicit positive health effects.


A medical professional is the only person qualified to recommend a particular dosage of resveratrol for you. For this reason, seek guidance from your physician before taking resveratrol supplements.

Dosing Guidelines

The University of Pittsburgh Medical Center reports that a reasonable dosage of resveratrol is approximately 500 mg per day. However, there is currently no established dosage recommendation for resveratrol.

Overall Safety

The safety of resveratrol supplements has yet to be fully evaluated in clinical trials. Thus, children, pregnant or breast-feeding mothers and people with kidney and liver disease shouldn't take resveratrol. In addition, resveratrol may mimic the action of estrogen, a sex hormone, in the body. Avoid taking resveratrol is you have a hormone-sensitive health condition, such as breast or ovarian cancer, because this supplement may worsen your symptoms.

Medication Interactions

Treatment with resveratrol supplements may not be appropriate if you're taking certain medications. Do not take resveratrol if you're taking an anticoagulant, such as heparin, warfarin, ibuprofen or aspirin. This treatment combination may increase your risk of experiencing bruising or bleeding complications. In addition, avoid using resveratrol in conjunction with medications that are broken down by your liver, such as fexofenadine, lovastatin and itraconazole. Resveratrol may reduce the rate at which your liver metabolizes these drugs, which can increase your likelihood of experiencing medication-specific side effects.