Bumps on the Edge of the Lips
The sudden occurrence of bumps on the edge of your lips can cause concern, particularly because bumps can indicate the herpes virus. Herpes is treatable, but cannot be cured. If you develop bumps on the lips, see your doctor for a proper evaluation and treatment.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Causes of Bumps
A variety of conditions, including acne and a kind of bacterial infection known as impetigo, cause bumps on the edge of your lips -- the area doctors refer to as the vermilion border of lip. However, if your bumps lack the features of acne, which is characterized by painful, plugged bumps, usually distributed over the face, shoulders and upper torso, or impetigo, which is characterized by easily-ruptured bumps that have a honey-crusted top, the bumps may be herpes cold sores.
About Herpes
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Herpes simplex virus type 1 causes herpes cold sores, although a small percentage of may be caused by herpes type 2 -- the virus most often associated with genital herpes. According to Timothy Berger in "Current Medical Diagnosis and Treatment," approximately 85 percent of the adult American population has been infected with type 1 herpes 1.
Time Course of an Outbreak
Berger explains that herpes outbreaks usually occur in the same place each time. Outbreaks begin with an abnormal sensation in the area of the outbreak, such as numbness, tingling or burning. The herpes lesions, described as a cluster of painful red blisters, appear either along with the abnormal sensation or shortly thereafter, within a day or two. The lesions eventually crust over and disappear, usually within one to two weeks.
- Berger explains that herpes outbreaks usually occur in the same place each time.
- The herpes lesions, described as a cluster of painful red blisters, appear either along with the abnormal sensation or shortly thereafter, within a day or two.
Diagnosis
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A physician diagnoses herpes by observation of the presence of clinical features of the disease, and may order laboratory tests to confirm the diagnosis. According to Lawrence Corey in "Harrison's Principles of Internal Medicine," laboratory confirmation is usually achieved by scraping a sample of tissue from the top of a herpes lesion and using a molecular test called "polymerase chain reaction" to amplify short segments of DNA specific to the herpes virus.
Treatment
Herpes treatment can be used to shorten the duration of an outbreak, or to prevent future outbreaks from occurring. In either case, the medicine of choice is one of a group of three antiviral drugs. These are acyclovir, valcyclovir and famciclovir. Over time, the frequency of outbreaks tends to lessen. However, transmission of herpes can still occur even in the absence of active herpes lesions.
- Herpes treatment can be used to shorten the duration of an outbreak, or to prevent future outbreaks from occurring.
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References
- "Current Medical Diagnosis and Treatment"; Stephen J. McPhee and Maxine A. Papadakis (editors); 2009
- "Harrison's Principles of Internal Medicine"; Anthony S. Fauci, Eugene Braunwald, Dennis L. Kasper, Stephen L. Hauser, Dan L. Longo, J. Larry Jameson, and Joseph Loscalzo (editors); 2008
- McQuillan G, Kruszon-Moran D, Flagg EW, Paulose-Ram R. Prevalence of herpes simplex virus type 1 and type 2 in persons aged 14–49: United States, 2015–2016. NCHS Data Brief. 2018;304.
- Tronstein E. Genital Shedding of Herpes Simplex Virus Among Symptomatic and Asymptomatic Persons With HSV-2 Infection. JAMA. 2011;305(14):1441. doi:10.1001/jama.2011.420
- World Health Organization (WHO). Herpes simplex virus. Updated January 31, 2017.
- Centers for Disease Control and Prevention. Genital Herpes - CDC Fact Sheet (Detailed). Updated January 31, 2017
- Centers for Disease Control and Prevention. Genital Herpes - CDC Fact Sheet. Updated August 28, 2017.
- Chun H, Carpenter R, Macalino G, Crum-Cianflone NF. The role of sexually transmitted infections in HIV-1 progression: A comprehensive review of the literature. Journal of Sexually Transmitted Diseases. 2012;2013(176459):1-15. doi:10.1155/2013/176459
- Heslop R, Roberts H, Flower D, Jordan V. Interventions for men and women with their first episode of genital herpes. Cochrane Database Syst Rev. 2016 Aug 30;(8):CD010684. doi:10.1002/14651858.CD010684.pub2
- Jin F, Prestage GP, Mao L, Kippax SC, Pell CM, et al. Transmission of herpes simplex virus types 1 and 2 in a prospective cohort of HIV-negative gay men: the health in men study. J Infect Dis. 2006 Sep 1;194(5):561-70.
- Schulte JM, Bellamy AR, Hook EW 3rd, Bernstein DI, Levin MJ, et al. HSV-1 and HSV-2 seroprevalence in the united states among asymptomatic women unaware of any herpes simplex virus infection (Herpevac Trial for Women). South Med J. 2014 Feb;107(2):79-84. doi:10.1097/SMJ.0000000000000062
Writer Bio
Alex Folkl has been writing for more than eight years and has had work appear in several peer-reviewed and non-peer-reviewed scientific publications. He has a bachelor's degree in biology, a master's degree in pathobiology, and an MD.