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At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- Hossain JL, Shapiro CM.The prevalence, cost implications, and management of sleep disorders: an overview.Sleep Breath. 2002 Jun;6(2):85-102.
- Hossain JL, Shapiro CM.The prevalence, cost implications, and management of sleep disorders: an overview.Sleep Breath. 2002 Jun;6(2):85-102.
- Zhdanova IV, Wurtman RJ, Regan MM, Taylor JA, Shi JP, Leclair OU. Melatonin treatment for age-related insomnia.J Clin Endocrinol Metab. 2001 Oct;86(10):4727-30.
- Zhdanova IV, Wurtman RJ, Regan MM, Taylor JA, Shi JP, Leclair OU. Melatonin treatment for age-related insomnia.J Clin Endocrinol Metab. 2001 Oct;86(10):4727-30.
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Lunesta with Melatonin
If you are having problems getting to sleep or staying asleep, you are not alone. Sleep disorders are a significant problem in the United States, affecting more than 70 million Americans, according to the American Academy of Sleep Medicine. Whether you suffer from a chronic long-term sleep disorder or experience occasional sleep problems, lack of sleep can leave you feeling anxious, cranky and unable to function.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Types of Sleep Disorders
There are more than 80 different sleep disorders, with insomnia being one of the most common. Insomnia affects about 60 million Americans each year, according to the American Sleep Association. Most often, insomnia is caused by another condition or problem, such as certain illnesses, pain, anxiety or depression. Insomnia can also be a side effect of some medications or be the result of too much caffeine, tobacco or alcohol.
- There are more than 80 different sleep disorders, with insomnia being one of the most common.
- Insomnia can also be a side effect of some medications or be the result of too much caffeine, tobacco or alcohol.
Melatonin for Insomnia
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Melatonin is a hormone naturally produced at night by your pineal gland that helps you to sleep. People with sleep problems often turn to over-the-counter melatonin supplements for help. In one study conducted by researchers at the Massachusetts Institute of Technology and published in the "Journal of Endocrinology and Metabolism" in 2001, it was found that melatonin improved sleep in people with insomnia age 50 or older 2. However, in general, data regarding the effectiveness of these supplements for insomnia are inconclusive, according to the National Sleep Foundation 2.
Dosing Considerations
With melatonin, it is important to take the right dosage for it to be effective. However, because melatonin is not a drug, it is manufactured in facilities that are not regulated by the United States Food & Drug Administration (FDA). As a result, the dosages listed on the product packages may not be controlled or accurate, meaning that you may not be taking the dose of melatonin that you think you are taking.
About Lunesta
Ambien Vs. Xanax For Sleeping
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Unlike melatonin, Lunesta is a prescription sleep medication approved by the FDA to help people fall asleep and stay asleep 2. Lunesta has been studied extensively in patients with chronic insomnia and is believed to work by interacting with brain receptors that respond to GABA, a chemical associated with sleep. Common side effects associated with Lunesta include: unpleasant taste in the mouth, dry mouth, morning drowsiness, dizziness, headache and common cold-like symptoms, according to the manufacturer.include:
- Common side effects associated with Lunesta include: unpleasant taste in the mouth
- dry mouth
- morning drowsiness
- dizziness
- headache
- common cold-like symptoms
- according to the manufacturer
Precautions
While either of these medications may be appropriate, do not attempt to combine Lunesta with melatonin without first consulting with your doctor. Combining any medication or herbal supplements can have dangerous consequences, so be sure to tell your doctor about all the products that you are taking. Also, prior to starting Lunesta, you should inform your doctor of any problems with alcohol or drug dependency because, like other sleep medications, Lunesta does carry a risk for dependency.
- While either of these medications may be appropriate, do not attempt to combine Lunesta with melatonin without first consulting with your doctor.
- Also, prior to starting Lunesta, you should inform your doctor of any problems with alcohol or drug dependency because, like other sleep medications, Lunesta does carry a risk for dependency.
Related Articles
References
- Hossain JL, Shapiro CM.The prevalence, cost implications, and management of sleep disorders: an overview.Sleep Breath. 2002 Jun;6(2):85-102.
- National Sleep Foundation: Melatonin and Sleep
- Zhdanova IV, Wurtman RJ, Regan MM, Taylor JA, Shi JP, Leclair OU. Melatonin treatment for age-related insomnia.J Clin Endocrinol Metab. 2001 Oct;86(10):4727-30.
- Ferracioli-oda E, Qawasmi A, Bloch MH. Meta-analysis: melatonin for the treatment of primary sleep disorders. PLoS ONE. 2013;8(5):e63773. doi:10.1371/journal.pone.0063773
- Auld F, Maschauer EL, Morrison I, Skene DJ, Riha RL. Evidence for the efficacy of melatonin in the treatment of primary adult sleep disorders. Sleep Med Rev. 2017;34:10-22. doi:10.1016/j.smrv.2016.06.005
- Esposito S, Laino D, D'alonzo R, et al. Pediatric sleep disturbances and treatment with melatonin. J Transl Med. 2019;17(1):77. doi:10.1186/s12967-019-1835-1
- Blasiak J, Reiter RJ, Kaarniranta K. Melatonin in retinal physiology and pathology: The case of age-related macular degeneration. Oxid Med Cell Longev. 2016;2016:6819736. doi:10.1155/2016/6819736
- Rossignol DA, Frye RE. Melatonin in autism spectrum disorders. Curr Clin Pharmacol. 2014;9(4):326-34. doi:10.2174/15748847113086660072
- Auger RR, Burgess HJ, Emens JS, Deriy LV, Thomas SM, Sharkey KM. Clinical practice guideline for the treatment of intrinsic circadian rhythm sleep-wake disorders: Advanced sleep-wake phase disorder (ASWPD), delayed sleep-wake phase disorder (DSWPD), non-24-Hour sleep-wake rhythm disorder (N24SWD), and irregular sleep-wake rhythm disorder (ISWRD). An Update for 2015: An American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2015;11(10):1199-236. doi:10.5664/jcsm.5100
- Hurtuk A. Melatonin: can it stop the ringing? Ann Otol Rhinol Laryngol. 2011 Jul;120(7):433-40 doi:10.1177/000348941112000703
- Andersen LP, Gögenur I, Rosenberg J, Reiter RJ. The safety of melatonin in humans. Clin Drug Investig. 2016;36(3):169-75. doi:10.1007/s40261-015-0368-5
- National Center for Complementary and Integrative Health. Melatonin: What you need to know. Updated October 2019.
- Costello RB, Lentino CV, Boyd CC, et al. The effectiveness of melatonin for promoting healthy sleep: a rapid evidence assessment of the literature. Nutr J. 2014;13:106. doi:10.1186/1475-2891-13-106
- Erland LA, Saxena PK. Melatonin natural health products and supplements: Presence of serotonin and significant variability of melatonin content. J Clin Sleep Med. 2017;13(2):275-281. doi:10.5664/jcsm.6462
- Kryger MH, et al. Principles and Practice of Sleep Medicine. Elsevier, 6th edition, 2016.
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Writer Bio
Based in Putnam County, N.Y., Susan Drew has been writing as a health care public relations and communications specialist since 1994. Her work has focused on raising awareness of various medical conditions, including severe obesity, fibromyalgia (chronic pain), movement disorders and bleeding disorders. She received her Bachelor of Science in journalism and media from Mercy College in Dobbs Ferry, N.Y.