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At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
- Cleveland Clinic: Shellfish Allergies
- “American Journal of Roentgenology, Radium Therapy and Nuclear Medicine,” Adverse Reactions to Intravascularly Administered Contrast Media. A Comprehensive Study Based on a Prospective Survey; W Shehadi; May 1975
- “American Journal of Roentgenology, Radium Therapy and Nuclear Medicine,” Adverse Reactions to Intravascularly Administered Contrast Media. A Comprehensive Study Based on a Prospective Survey; W Shehadi; May 1975
- "Allergy"; Anaphylactoid and Anaphylactic Reactions to Iodinated Contrast Material; D. Laroche; 1999
- "Allergy"; Anaphylactoid and Anaphylactic Reactions to Iodinated Contrast Material; D. Laroche; 1999
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
If You Are Allergic to Shellfish Can You Take Pills With Iodine?
People with shellfish allergy often avoid iodine products because of a commonly held belief that people with a shellfish allergy also have an allergy to iodine. Having a shellfish allergy, however, does not mean you’re also allergic to iodine, according to Cleveland Clinic 23. It is, however, possible to have an allergy to both shellfish and iodine. Ask your doctor if you should use iodine products if you have an allergy.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Shellfish Allergies
Shellfish allergies can occur to any crustacean; having an allergy to one type of shellfish does not mean you’ll have an allergy to all of them 3. You may develop a shellfish allergy even if you’ve eaten shellfish before without a problem. Allergies to shellfish appear to occur as a reaction to tropomyosin, a muscle protein in shellfish 3. Shellfish make the list of the eight substances most likely to cause an allergic reaction. While food labels must list shellfish as an ingredient due to its high allergy potential, labels do not need to state whether other foods were processed in the same plant as shellfish.
Iodine Allergies
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Iodine reactions may not actually be allergies, which are immune responses to an allergen. Instead, iodine reaction may be idiosyncratic reactions better termed as pseudo allergic or allergy-like reactions. Skin reactions to iodine occur rarely and are usually due to skin irritation rather than an allergic reaction. Systemic effects rarely occur from this type of reaction, the University of California San Francisco states 1.
- Iodine reactions may not actually be allergies, which are immune responses to an allergen.
- Skin reactions to iodine occur rarely and are usually due to skin irritation rather than an allergic reaction.
Cross Reactions
According to University of California San Francisco, around 5 percent of people who underwent contrast iodine dye in a large study experienced some type of reaction 1. The risk of reaction in people with seafood allergy was three times higher than the general population, while people with an allergy to eggs, milk or chocolate had 2.9 times the risk. People with fruit and strawberry allergies had 2.6 times the risk, while people with asthma had 2.2 time increased risk. In other words, having any allergy increases your risk of having an allergic reaction to iodine dye. Around 85 percent of people with shellfish allergy who receive iodine dye will not have a reaction, the UCSF states.
- According to University of California San Francisco, around 5 percent of people who underwent contrast iodine dye in a large study experienced some type of reaction 1.
- The risk of reaction in people with seafood allergy was three times higher than the general population, while people with an allergy to eggs, milk or chocolate had 2.9 times the risk.
Considerations
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If you’ve always thought you couldn’t take or use iodine because of a shellfish allergy, you may hesitate to take anything containing iodine. Talk with your doctor about the risks and benefits of taking iodine. As few as 2 to 3 percent of people who have reactions to dyes used in contrast studies have an actual allergy to the dye, according to a French study published in the 1999 issue of “Allergy.”
Related Articles
References
- University of California San Francisco: Iodine Allergy and Contrast Administration
- Women's Health Resource; Does Iodine Allergy Mean a Shellfish Allergy Too?; Frederick R. Jelovsek M.D., M.S.
- Cleveland Clinic: Shellfish Allergies
- “American Journal of Roentgenology, Radium Therapy and Nuclear Medicine,” Adverse Reactions to Intravascularly Administered Contrast Media. A Comprehensive Study Based on a Prospective Survey; W Shehadi; May 1975
- "Allergy"; Anaphylactoid and Anaphylactic Reactions to Iodinated Contrast Material; D. Laroche; 1999
- Food Allergy Research & Education. Shellfish Allergy.
- Khora SS. Seafood-Associated Shellfish Allergy: A Comprehensive Review. Immunol Invest. 2016;45(6):504-30. doi: 10.1080/08820139.2016.1180301
- Food and Drug Administration. What You Need to Know about Food Allergies.
Writer Bio
A registered nurse with more than 25 years of experience in oncology, labor/delivery, neonatal intensive care, infertility and ophthalmology, Sharon Perkins has also coauthored and edited numerous health books for the Wiley "Dummies" series. Perkins also has extensive experience working in home health with medically fragile pediatric patients.