What does fact checked mean?
At Healthfully, we strive to deliver objective content that is accurate and up-to-date. Our team periodically reviews articles in order to ensure content quality. The sources cited below consist of evidence from peer-reviewed journals, prominent medical organizations, academic associations, and government data.
The information contained on this site is for informational purposes only, and should not be used as a substitute for the advice of a professional health care provider. Please check with the appropriate physician regarding health questions and concerns. Although we strive to deliver accurate and up-to-date information, no guarantee to that effect is made.
Lipids, or fats, are an important source of energy in the human body. Lipids in the body are constantly broken down, metabolized and used for energy production and replenished from food. The Merck Manuals Online Medical Library underlines that specific types and amounts of enzymes are required for the body to be able to balance storage and breakdown of fats. Imbalances or abnormal production of these enzymes can lead to an accumulation of fats that can damage many organs in the body. Other lipid-related diseases include the inability to convert stored fats to energy. The lipid diseases are inherited and can cause permanent damage and even death.
If you are experiencing serious medical symptoms, seek emergency treatment immediately.
Gaucher's disease is the most common type of lipid storage disease. It is by caused by a deficiency of an enzyme called glucocerebrosidase. In this inherited disease fat collects in the brain, lungs, liver, spleen, kidneys and bone marrow. This causes the organs to enlarge, swell and malfunction as well as bone disorders and painful lesions. The National Institute of Neurological Disorders and Stroke mentions that there are several types of Gaucher’s disease and males and females are affected equally. The disease is most common in Ashkenazi (Eastern European) Jews. Children with an infantile form of this disease have an enlarged spleen, severe nervous disorders and usually die within a year. The chronic form of Gaucher’s disease is the most common and is most commonly diagnosed in childhood.
Tay-Sachs disease is a lipid disorder that is inherited. It causes a buildup of fats in the tissues that is usually fatal early in life. The disease is most common among family members of Eastern European origin. Effects of this lipid disease appear early, causing intellectual disability and loose muscle tone in children that progressively worsens. Other signs and symptoms include muscle spasms, paralysis, dementia and blindness. There is presently no cure or treatment and in most cases children with Tay-Sachs do not live past the age of five years. Prevention of Tay-Sachs includes genetic counseling, during which parents can find if they are carring the gene for this disease before conception and by amniocentesis during pregnancy.
Lipid Oxidation Disorder
Lipid or fatty acid oxidation disorders are caused by a deficiency or lack of the enzymes needed to break down fats to produce energy 1. This decreases energy in the body and leads to delayed physical and mental development, according to the National Institute of Neurological Disorders and Stroke.
Lipids, or fats, are an important source of energy in the human body. Imbalances or abnormal production of these enzymes can lead to an accumulation of fats that can damage many organs in the body. The National Institute of Neurological Disorders and Stroke mentions that there are several types of Gaucher’s disease and males and females are affected equally. The disease is most common in Ashkenazi Jews. It causes a buildup of fats in the tissues that is usually fatal early in life.
- Jason Reed/Photodisc/Getty Images