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Diseases Associated With Tingling Sensations

Numerous diseases can cause tingling sensations. According to MedlinePlus from the National Institutes of Health, tingling sensations in the extremities--or other parts of the body--are often accompanied by numbness or decreased sensation, and both tingling and numbness are abnormal sensations that indicate an underlying health problem or disease 1. MedlinePlus states that treatment for numbness and tingling can eliminate the sensations or prevent them from getting worse 1.

Is This an Emergency?

If you are experiencing serious medical symptoms, seek emergency treatment immediately.

Pernicious Anemia

According to the National Heart Lung and Blood Institute, or NHLBI, pernicious anemia is a condition in which a person's body is unable to manufacture sufficient amounts of healthy red blood cells because there is not enough vitamin B12 present 23. The NHLBI states that a person with pernicious anemia is unable to absorb sufficient vitamin B12 from food because of a lack of intrinsic factor--a glycoprotein synthesized by the stomach's parietal cells 3. The lack of intrinsic factor results in vitamin B12 deficiency, along with numbness and tingling in the hands and feet 1.


Causes of Tingling in the Leg & Foot

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Carpal Tunnel Syndrome

According to the National Institute of Neurological Disorders and Stroke, or NINDS, carpal tunnel syndrome occurs when the median nerve--a large nerve coursing through the forearm and into the hand--becomes impinged at the wrist as it travels through the carpal tunnel 4. The carpal tunnel is a narrow passageway through which numerous tendons and the median nerve pass. The NINDS states that carpal tunnel symptoms often manifest gradually, and tingling sensations, along with burning or itching, are sometimes among the first symptoms reported by a person with carpal tunnel syndrome.